Dr. Xing and Zhao et al. of Michigan Tech University have published a paper entitled: “Aligned Nanofibrous Cell-Derived Extracellular Matrix for Anisotropic Vascular Graft Construction”
The research group was successful in generating a vascular graft with biomimetic circumferential tensile strength and expression of smooth muscle cell specific genes over static culture.
In previous studies, fibroblast cells were used to create vascular grafts by wrapping a decellularized fibroblast seeded matrix sheet around a temporary mandrel into tubes.
Visit the Research Team’s Website