Category: Research

Sangyoon Han on Cell Adhesion

Sangyoon Han
Sangyoon Han

Sangyoon Han (BioMed) was quoted by The Scientist in a story about a recent study reporting the promotion of cellular adhesion by the adaptor protein Cas. The story involves the migration of cells during development, immune defense, and tumorigenesis. Cells need to form and dismantle attachments with the extracellular matrix and other cells.

Researchers reported that the adaptor protein Cas promoted the initiation of cellular adhesion.

Sangyoon Han, not involved in that study, commented on the sparseness of studies involving premechanosensitive processes that act as a seed for the original binding of this mechanosensitive binding. He emphasized the importance of further research and how people can now change their perspective on the focal adhesion assembly.

Han’s research involves mechanobiology, traction force by a living cell, and cell adhesion and migration. He is an assistant professor in Biomedical Engineering.

Read more at The Scientist, by Shelby Bradford.

Integrated Molecular Innovations Wins Individual Investment and Cash Prize


Last week, Huskies took their business pitches on the road and won big!

Graduate student Rourke Sylvain (biomedical engineering) and Ali Dabas ‘23 (B.S. Biomedical Engineering) pitched imi (integrated molecular innovations) at the renowned Rice Business Plan Competition. They won $25,000 in prize money for the best pediatric device, sponsored by Southwest National Pediatric Device Innovation Consortium (SWPDC). Sylvain, founder and CEO, and Ali Dabas, co-founder and CTO, pitched a wearable device that revolutionizes health care by eliminating the need for centralized clinical testing. They pitched in two categories. The shorter elevator pitch can be viewed on YouTube.

Congratulations to our student teams! We are proud of your hard work!

By Husky Innovate, Pavlis Honors College.

The Rice Business Plan Competition exists so that student founders pushing to create new possibilities in technology, energy, healthcare and more can surround themselves with a powerful network; learn what it takes to secure investor funding.

Play Integrated Molecular Innovations video
Preview image for Integrated Molecular Innovations video

Integrated Molecular Innovations

Health Research Institute 2023 Summer Fellowship Award for Mohanish Chandurkar

Mohanish Chandurkar Poster
Mohanish Chandurkar stands by his poster at the 2022 Graduate Research Colloquium at Michigan Tech.

The Health Research Institute (HRI) at Michigan Tech is pleased to announce Summer Fellowship awardees for 2023. Congratulations to all recipients!

HRI Summer Fellowship awardees are:

  • Alexander Apostle, Chemistry
  • Mohanish Chandurkar, Biomedical Engineering
  • Catherine Rono, Biological Sciences

HRI Student Fellowships are awarded three times a year. More information can be found on the HRI website.

By the Health Research Institute.

Rourke Sylvain Places in High Tech Growth Category

Congrats to Michigan Tech’s New Venture Challenge Competitors!

Central Michigan University (CMU) and Michigan Tech collaborate each year to offer Michigan Tech students a chance to compete in CMU’s New Venture Challenge (NVC). This gala event provides an opportunity for students at both universities to present their new ventures and to network with prospective investors, mentors and partners. Student contestants compete for over $60,000 in prizes and in-kind services.

On Friday (April 21, 2023), two Michigan Tech teams—Bayle Golden, a graduate student in engineering management, and Rourke Sylvain, a graduate student in biomedical engineering—pitched their innovations in the seven-minute pitch category at NVC and won. Congrats go to both teams! NVC awards are as follows:

  • Bayle Golden (engineering management) won first place in the Social Mission category and received $10,000. Golden won an additional $10,000 for Best Overall Venture for a total of $20,000!
    • “At STEMPOWER we are working to create an integrative STEM experience for young girls through a physical toy line and online STEM community. We believe that we can change the STEM landscape and empower an entire generation of youth.”
  • Rourke Sylvain won third place in the High Tech High Growth category, receiving $2,0000. Sylvain’s pitch was “imi (integrated molecular innovations),” an electrochemical biosensor for T4 detection.
    • “imi revolutionizes health care by eliminating the need for centralized clinical testing. We develop bio wearable devices that provide patients the ability to monitor their hormone levels continuously.”

Congratulations to our Husky Innovate student teams for all their hard work! We are proud of your perseverance and determination to take your ideas to the next level. Your solutions have the potential to make a positive impact for so many.

In preparing for the NVC, the students participated in a number of Husky Innovate workshops and prep sessions. Thank you to the Husky Innovate Teaching Team and the MTEC SmartZone, specifically Jason Mack and Patrick Visser, for their guidance to our teams. A special thanks to Michigan Tech alum Joe Corso ’77 (B.S. Electrical Engineering) for coaching our students and sharing his time and entrepreneurial expertise.

Thanks go to Jim Baker, associate vice president for research administration, and Len Switzer, associate director of partnerships for Enterprise and Senior Design, who attended NVC to support teams, represent Tech and build connections. Thanks to our Husky Innovate sponsors: the Pavlis Honors College, the Office of Innovation and Commercialization, and the College of Business, for their commitment to our students. Lastly, thank you to CMU and our host Julie Messing, director of the Isabella Bank Institute for Entrepreneurship, for the warm welcome and continued partnership.

By Husky Innovate, Pavlis Honors College.

Michigan Tech Entrepreneurs Pitch Off-Site This Week

Two Michigan Tech student teams will pitch their innovations at offsite pitch competitions this week. Jordan Craven will pitch Sizelogic at TCNewTech and Rourke Sylvain and Ali Dabas will pitch imi at the prestigious Rice Business Plan Competition. Best of luck to both teams!

Jordan Craven is the founder and CEO of Sizeologic. Sizelogic is committed to improving the online clothing retail industry by providing a comprehensive solution that makes it easier for customers to find clothes that fit them perfectly. Craven is in her fourth year of studying management in information systems and computer science at Michigan Tech. View her TCNewTech collegiate pitch tomorrow (May 9).

The TCNewTech University Pitch Showdown is part of the Northern Michigan Startup Week, a weeklong celebration of entrepreneurship, innovation and the startup community in Northern Michigan.

Rourke Sylvain, founder and CEO of imi (integrated molecular innovations), and Ali Dabas, imi’s co-founder and CTO, are pitching a biowearable device that revolutionizes healthcare by eliminating the need for centralized clinical testing. Their device will provide patients with the ability to monitor their hormone levels continuously.

Sylvain is currently completing an M.S. in biomedical engineering and an M.S. in data science and is transitioning into the Ph.D. program for biomedical engineering at Michigan Tech. Dabas completed a B.S. in biomedical engineering (’23) and has an associate’s degree in math and science.

At the Rice Business Plan Competition, they will present their elevator pitch on May 11 at 6 p.m. and participate in the live finals 15-minute pitch on May 13 at 12 p.m., both of which can be watched on YouTube or at the Rice Business Plan Competition website.

By Husky Innovate, Pavlis Honors College.

Related

Biomedical Engineering Graduate Students Place at Graduate Research Colloquium 2022

Fatemeh Razaviamri poster with two people standing by it.
Fatemeh Razaviamri Poster
Brennan Vogl by his poster.
Brennan Vogl Poster
Mohanish Chandurkar by his poster.
Mohanish Chandurkar Poster

The Graduate Research Colloquium 2022 was held March 29 and 30. Graduate Student Government (GSG) would like to thank everyone who made the event possible. Over the two days, we had 50 poster presentations and 49 oral presentations.

The winners are as follows:

Poster Presentations

  • Third Place: Mohanish Chandurkar (Biomedical Engineering), “Shear stress sensing on endothelial cells using traction force microscopy (TFM)”
  • Second Place (tie): Laura Schaerer, “Division of Labor in Polyethylene Terephthalate Degrading Microbial Consortia”
  • Second Place (tie): Brennan Vogl (Biomedical Engineering), “Effect of aortic curvature on bioprosthetic aortic valve performance”
  • First Place: Arslan Amer, “Selenoprotein Sepp1 Determines Cysteine Dependence in Pancreatic Cancer”

Oral Presentations

Due to an unlikely four-way tie, we have decided to present the awards to our top four presenters in no particular order:

  • Arslan Amer, “Selenium and Cysteine in Pancreatic Cancer Therapy”
  • Fatemeh Razaviamri (Biomedical Engineering), “Moisture-Activated Antiviral Coating based on Mussel Adhesive Chemistry”
  • Rishi Babu, “Study of a source rich region to understand the origin of PeVatrons”
  • Isaac Wedig, “A Practical Application of Blood Flow Restriction Exercise”

A hearty congratulations to all the winners at this year’s colloquium. GSG would like to thank everyone — presenters, judges, volunteers and GSG supporters — for making this a great event!

View the Photo Gallery

By Graduate Student Government.

Sangyoon Han Joins the Institute of Computing and Cybersystems

Sangyoon Han
Sangyoon Han

Sangyoon Han, an assistant professor in Michigan Tech’s Biomedical Engineering department, and an affiliated assistant professor in Mechanical Engineering-Engineering Mechanics, recently joined the multi-disciplinary Institute of Computing and Cybersystems (ICC) and its Data Sciences research group.

Han’s primary research interests are in mechanobiology, cell migration, and image data modeling, and he’s looking for collaborators. His research goals include applying computer vision to microscopic images to capture meaningful information, and Han invites researchers and students to contact him to discuss potential research opportunities. Learn more about Sangyoon Han in the blog post.

By Institute of Computing and Cybersystems.

Lee Attends Meeting of the Adhesion Society

AS 44th Annual Meeting

Bruce Lee (BioMed) and former PhD student Rattapol Pinnaratip (BioMed) attended the 44th Annual Meeting of the Adhesion Society virtually on February 22-25, 2021. Pinnaratip gave a talk entitled “Utilization of Hydrogen Peroxide Byproduct in Catechol-Based Adhesive for Dermal Wound Healing.”

Lee gave a talk entitled “Antimicrobial Property of Biomimetic Halogenated Catechol Adhesive Moiety”. Lee also chaired two sessions entitled “Biomedical Adhesion” and “Organismal Adhesion”.

Position Openings in the Brain Stimulation Lab

Brain Sections

Please email Dr. Traci Yu (chunxiuy@mtu.edu) in Biological Sciences, including a copy of your CV for any of the following positions:

Graduate Students

We currently have openings for highly-motivated graduate/master students with interests and/or experience in neuroscience, engineering, or computer science. Previous experience in computational modeling is beneficial.

The focus of this position is on developing novel strategies to improve therapeutic efficiency and efficacy of brain stimulation in neurological disorders using various experimental and computational approaches.

Graduate students will be accepted into the Department of Biomedical Engineering through the appropriate graduate admissions process and start in the fall of 2021. Those interested should hold a bachelor’s or master’s degree in Biomedical Engineering, Electrical Engineering or a related field and contact Dr. Yu first before applying.

Undergraduate Research Assistants

We are also seeking motivated undergraduates with knowledge of engineering, biology, or computer science. Students will acquire knowledge and hand-on skills in brain dissection, electrophysiology, behavioral testing, and computational data analysis. Students with MATLAB programming skill are preferred.

Graduate Research Assistant Needed for the Biofluids Lab

Biofluids Lab

Position is Closed

The Biofluids Laboratory at the Biomedical Engineering Department of Michigan Technological University (Houghton, Michigan) has an opening for a graduate research assistant (PhD) starting January 2021.

The candidate will contribute to:

  • The design and implementation of cardiovascular devices.
  • Conducting experimental and computational studies on various congenital and adult cardiovascular models.
  • Image reconstruction and processing by using and expanding existing tools and development of novel methodologies.

Applicants should hold a bachelor’s or master’s degree in Mechanical Engineering, Biomedical Engineering, or a related field.

To apply, please submit applications here. In addition, send a copy of your CV and the contact information of three references to Dr. Hoda Hatoum (hhatoum@mtu.edu). Review of applications will begin immediately.