Author: Yin-Yin Tan

This position is part of the National Institute of Standards (NIST) Professional Research Experience (PREP) program. National Institute of Standards (NIST) Professional Research Experience (PREP) program invites applicants in support of research in assay development for cell-free expression systems. NIST recognizes that its research staff may wish to collaborate with researchers at academic institutions on specific projects of mutual interest, thus requires that such institutions must be the recipient of a PREP award. The PREP program requires staff from a wide range of backgrounds to work on scientific research in many areas. Employees in this position will perform technical work that underpins the scientific research of the collaboration.

Research Title: Research Scientist for Cell-free Expression System Metrology

The work will entail:

The Materials Measurement Laboratory of the National Institute of Standards and Technology is seeking qualified U.S. Citizens to support the Cellular Engineering Group and NIST Engineering Biology Program, by leading projects to develop measurement assurance for cell-free expression systems from diverse samples, including reconstituted and microbial samples. Leads the development of characterization assays for cell-free systems. Assists automating reagent preparation, cell-free reaction assembly, and characterization, using the NIST Living Measurement Systems Foundry (LMSF) and other laboratory
automation. Analyzes experimental and simulation data, including uncertainty and other statistical analyses. Documents and manages protocols, data, and analyses. Regularly presents and discusses
progress with the larger organization.

U.S. Citizen Preferred

Key responsibilities:

• Leads, plans, and carries out difficult and complex assignments in cell-free expression systems and RNA circuits with limited supervision.
• Completed work has a sound overall approach and effectively meets requirements.
• Communicates effectively with peers and stakeholders to plan share work outputs.

Qualifications:

• A Doctoral degree in chemical engineering, bioengineering, cell biology, chemistry, physics, synthetic biology, or a related field.
• Demonstrated knowledge of cell biology, molecular biology, microbial culture, reconstituted and lysate-based cell-free expression systems, and synthetic/engineering biology.
• Demonstrated leadership and management of technical projects and programs.
• 5 years of relevant experience.
• Strong oral and written communication skills.

Please upload the following (preferably in a single PDF) with your application:

• CV/Resume

Privacy Act Statement

Authority: 15 U.S.C. § 278g-1(e)(1) and (e)(3) and 15 U.S.C. § 272(b) and (c)

Purpose: The National Institute for Standards and Technology (NIST) hosts the Professional Research Experience Program (PREP) which is designed to provide valuable laboratory experience and financial assistance to undergraduates, post-bachelor’s degree holders, graduate students, master’s degree holders, postdocs, and faculty.

PREP is a 5-year cooperative agreement between NIST laboratories and participating PREP Universities to establish a collaborative research relationship between NIST and U.S. institutions of higher education in the following disciplines including (but may not be limited to) biochemistry, biological sciences, chemistry, computer science, engineering, electronics, materials science, mathematics, nanoscale science, neutron science, physical science, physics, and statistics. This collection of information is needed to facilitate administrative functions of the PREP Program.

Routine Uses: NIST will use the information collected to perform the requisite reviews of the applications to determine eligibility, and to meet programmatic requirements. Disclosure of this information is also subject to all the published routine uses as identified in the Privacy Act System of Records Notices: NIST-1: NIST Associates.

Disclosure: Furnishing this information is voluntary. When you submit the form, you are indicating your voluntary consent for NIST to use of the information you submit for the purpose stated.

• Announcement and Application

This position is part of the National Institute of Standards (NIST) Professional Research Experience (PREP) program. National Institute of Standards (NIST) Professional Research Experience (PREP) program invites applicants in support of research in material flammability testing and modeling. NIST recognizes that its research staff may wish to collaborate with researchers at academic institutions on specific projects of mutual interest, thus requires that such institutions must be the recipient of a PREP award. The PREP program requires staff from a wide range of backgrounds to work on scientific research in many areas. Employees in this position will perform technical work that underpins the scientific research of the collaboration.

Research Title: Material Flammability Testing and Modeling

U.S. Citizen Preferred

The work will entail:

The fire modeling community is working to predict material flammability behavior quantitatively (e.g., ignition, burning rate, fire growth). State-of-the-art fire models require input parameters (material properties) that describe combustible solids’ decomposition reaction mechanism (and associated kinetics and thermodynamics) and relevant heat/mass transport properties.

To address this need, the NIST Fire Research Division has been developing experimental and analytical tools to calibrate these material properties and validate their ability to predict flammability response across a range of configurations/scales (i.e., mg-scale thermal decomposition, g-scale gasification/burning, and flame spread over panels between 0.5 m and 2.5 m tall).

Working with the project leader, the researcher will develop and then lead the execution of experiments associated with the following tasks:

• Developing a material flammability database that maintains the tools (experimental and analytical), measurement data (for model calibration and validation), and material property sets necessary to quantitatively predict material flammability behavior (e.g., ignition, steady burning, and fire growth).

• Conduct and analyze the data from bench to full-scale thermal and fire property tests for fire model calibration and validation.

• Produce and present publications on research findings.

Key responsibilities:

• Assisting in the development, implementation, and leadership of a research plan to quantify fire growth rate, flame structure, condensed-phase response, and mass loss & heat release rate of combustible solids burning at the intermediate scale (emphasis on materials that deform; e.g., due to melt flow or charring/smoldering).
• Applying and advancing state-of-the-art techniques to quantify the mechanisms controlling material flammability; iterative development and implementation of analytical tools to process these results.
• Development and execution of plans for transferring NIST research through meetings, workshops, and conferences; preparing and presenting measurement results (oral presentations and written reports).

Qualifications:

• U.S. Citizen Preferred.
• PhD in Engineering (fire protection, materials science, mechanical), Chemistry, Physics, or a related field
• 2+ year(s) of relevant lab experience (i.e., experimental design and testing).
• Excellent oral and written communication skills.
• Excellent time management and organizational skills.
• Proficiency in programming/data analysis tools (e.g., Excel, MATLAB, Python, R).
• Ability to work independently and as part of a team to learn new activities and skills.
• Ability and enthusiasm to help lead early-career researchers as part of a research team.

Please upload the following (preferably in a single PDF) with your application:

• CV/Resume

Privacy Act Statement

Authority: 15 U.S.C. § 278g-1(e)(1) and (e)(3) and 15 U.S.C. § 272(b) and (c)

Purpose: The National Institute for Standards and Technology (NIST) hosts the Professional Research Experience Program (PREP) which is designed to provide valuable laboratory experience and financial assistance to undergraduates, post-bachelor’s degree holders, graduate students, master’s degree holders, postdocs, and faculty.

PREP is a 5-year cooperative agreement between NIST laboratories and participating PREP Universities to establish a collaborative research relationship between NIST and U.S. institutions of higher education in the following disciplines including (but may not be limited to) biochemistry, biological sciences, chemistry, computer science, engineering, electronics, materials science, mathematics, nanoscale science, neutron science, physical science, physics, and statistics. This collection of information is needed to facilitate administrative functions of the PREP Program.

Routine Uses: NIST will use the information collected to perform the requisite reviews of the applications to determine eligibility, and to meet programmatic requirements. Disclosure of this information is also subject to all the published routine uses as identified in the Privacy Act System of Records Notices: NIST-1: NIST Associates.

Disclosure: Furnishing this information is voluntary. When you submit the form, you are indicating your voluntary consent for NIST to use of the information you submit for the purpose stated.

• Announcement and Application