Ph.D. candidate Sodiq Waheed (Chem), postdoctoral scholar Rajeev Ramanan (Chem), Ph.D. candidate Shobhit Chaturvedi (Chem), Tatyana Karabencheva-Christova (Chem) and Christo Christov (Chem) were listed as co-authors in an article titled “Role of Structural Dynamics in Selectivity and Mechanism of Non-heme Fe(II) and 2-Oxoglutarate-Dependent Oxygenases Involved in DNA Repair” published in ACS Central Science.
Chris Schofield of the University of Oxford and Nicolai Lehnert of the University of Michigan were also listed as co-authors on the article.
Led by Karabencheva-Christova and Christov, the research group revealed the vital effect of DNA conformational dynamics on the catalytic mechanism of the bacterial non-heme Fe(II)- and 2-Oxoglutarate-Dependent DNA Demetylase AlkB and the human homolog AlkBH2. The article was also selected for a supplementary cover.