Chemistry Newsblog

Author: Steve Mintz

Chemistry in Print

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Chemistry Team Publishes in JACS Au

Congratulations to the team including Department of Chemistry Ph.D. students Shobhit Chaturvedi (lead author), Bathir Sathik, and Sodiq Waheed, and undergraduate students Jon Wildey (chemical engineering) and Cait Warner (biological sciences), and led by Christo Christov and Tatyana Karabencheva-Christova (Chem), whose article was published in JACS Au.

The article is titled “Can Second Coordination Sphere and Long-Range Interactions Modulate Hydrogen Atom Transfer in a Non-Heme Fe(II)-Dependent Histone Demethylase?” Christopher Schofield of the University of Oxford, U.K., is also a co-author of the article. This research is supported by NIH grant GM139118.

The study reveals how residues in the second coordination sphere and beyond drive and control the reactivity of the non-heme iron(iv)-oxo complex of the histone demethylase PHF8 to perform the key hydrogen atom abstraction reaction in its catalytic mechanism.

Chemistry Team Publishes in Chemistry – A European Journal

Ph.D. student Sodiq Waheed (chemistry) and Christo Christov (Chem) are participants in a collaborative experimental/computational study led by Nicolai Lehnert at the University of Michigan which was published in Chemistry – A European Journal.

The study, titled “YfeX – A New Platform for Carbene Transferase Development with High Intrinsic Reactivity,” focuses on a redesign of YfeX enzyme as a platform for carbene transferase reactions.

Victor Sosa Alfaro (lead author) and Hannah Palomino of the University of Michigan and Anja Knorrscheidt and Martin Weissenborn of the Martin Luther University of Halle-Wittenberg, Germany, are co-authors of the manuscript.

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NOBCChE Brings Chemistry to Baraga Youth

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As part of its goal of outreach to the local community and promoting STEM — and chemistry in particular — to young people from low socioeconomic backgrounds, the MTU student chapter of the National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCChE) recently organized an outreach event for the high school chemistry class of Baraga Area Schools.

A hands-on explorative activity on paper chromatography was the focus of the outreach event, introducing students to the wide array of applications of chromatography as a separation technique. After introducing students to the concept of chromatography, students were able to see it come alive by separating various colored inks into their constituents. After this introductory activity, students used their chromatography skills to do some forensic analysis on an ink sample and pens from various “suspects” to see who was responsible for defacing a very expensive book from the school library. Finally, the volunteers engaged the students in a discussion to synthesize their observations and draw out the big scientific ideas.

The students were very focused, interactive, and excited about the activities. Some of them, when asked to comment on the activity, noted that it was engaging and insightful. One even said, “This is so cool and fun.”

NOBCChE hopes to continue to get out in the local schools and open up the wide world of chemistry to area students. See photos from the outreach event.

Michigan Tech graduate students in chemistry and chemical engineering — Sodiq Waheed, Kobina Ofori, Parya Siacheshm, and Monica Nyansa — organized this outreach event with NOBCCHE advisor Jeremy Brown (Chem). The event was funded by the NOBCChE K-12 Initiative.

This post was originally published in the Michigan Tech Chemical Engineering News blog on May 26, 2022.

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