Author: Sue Hill

Sue Hill is the Digital Content Manager for the College of Engineering.

Natalie Nold Awarded at 2023 AIChE Annual Meeting

Natalie Nold is the recipient of the 2023 Separations Division Graduate Student Research Award for her outstanding work in the area of bioseparations. Nold is a Ph.D. student working in Caryn Heldt’s bioseparation lab.

The award was presented at the Separations Division Dinner at the AIChE Annual Meeting. The 2023 AIChE Annual Meeting was held on November 5–10 in Orlando, FL.

The Separations Division Graduate Student Research Award recognizes outstanding graduate students in the following areas:

  • Distillation and Absorption
  • Crystallization and Evaporation
  • Extraction
  • Membrane-Based Separations
  • Adsorption and Ion Exchange
  • Fluid-Particle Separations
  • Bioseparations

Recipients receive a plaque and $200 for each award. For consideration a single paper must be submitted that contributes to separations fundamentals or applications. The paper must report on research, investigation or design, and must be part of the student’s work for a graduate degree.

Chemical Engineering External Advisory Board Poster Session 2023

The poster session took place on the third floor of the ChemSci building on October 20, with prizes for student organization, undergraduate research, and graduate research.

First Place Graduate Research: Hunter Stoddard, Microbial Community Forms Biofilm in Hybrid Chemical-Biological Upcycling Process

Second Place Graduate Research: Grace Dykstra, Low-cost, Stable, and Selective Synthetic biosensors for Lactate Detection

First Place Undergraduate Research: Prajeet Kadam, Quantifying Dielectrophoretic Responses of RAW 264.7 Macrophages: Baseline and LPS Activated Cells

Second Place Undergraduate Research: Morgan Redding, Low-cost, Stable, and Selective Synthetic biosensors for Lactate Detection

First Place Student Organization: Addymae Palecek, The American Institute of Chemical Engineers (AIChE)

Graduate Research

Iman Najafipour by his poster.
Iman Najafipour by his poster.

Poster #1

Optimization of water extraction conditions for removal of yeast inhibitory compounds from switchgrass

Authors: Iman Najafipour, Dr. Rebecca Ong

Abstract: Drought-stressed switchgrass, a potential bioenergy feedstock, often exhibits elevated yeast inhibitor. Effective removal of inhibitory compounds enhances sugar conversion to bioethanol, maximizing energy production, yield, and cost-efficiency. The objective is to optimize Accelerated Solvent Extraction (ASE) for efficient yeast inhibitor extraction, thereby increasing yield while minimizing water consumption. The impact of temperature (A), time (B), and extraction cycles (C) on the extracted mass was investigated using a Box-Behnken model. A, B, C, AB, BC, and CC terms influenced the extraction, aligning well with experimental data. This ongoing project examines how extraction conditions affect yeast inhibition, and fermentation.

Hunter Stoddard by his poster.
Presenter Hunter Stoddard by his poster.

Poster #2: First Place Graduate Research

Microbial Community Forms Biofilm in Hybrid Chemical-Biological Upcycling Process

Authors: Hunter Stoddard, Dr. Rebecca Ong

Abstract: Biofilms can form on process equipment and make harvest of the cell biomass challenging. In this study, a microbial consortium was grown on products from pyrolysis and from depolymerization using ammonium hydroxide. Bioreactor conditions were varied to determine the highest production of biomass and the proportion of biomass as a biofilm. It was determined that the most biomass was produced at 30°C, pH 7, 100 rpm agitation, and 10 sL/h airflow. Reducing temperature and increasing aeration had the largest impact on biofilm formation where the percentage of biomass that was attached as biofilm was 20.8% at 30°C and 27.8% at 10 sL/h airflow.

William Hanson by his poster.
William Hanson by his poster.

Poster #3

Prediction of ex-situ Direct Carbonation of Natural Minerals using Machine Learning Algorithms

Authors: William Hanson, Dr. Lei Pan

Abstract: Mineral carbonation is a carbon fixation method in which the atmospheric CO2 reacts with alkaline oxide/silicate minerals to form carbonate minerals. In this work, mineral carbonation efficiency for the direct carbonation of various natural silicate minerals was investigated. In addition, carbonation efficiency was modeled using machine learning techniques including gradient boost, random forest, artificial neural network, K-nearest neighbor, and self-building neural network. Among models tested, gradient boost had the lowest error while artificial neural networks had the highest error. The present result is to ensure that industrial-scale carbonation operations will be optimally designed.

Idris Tohidian by his poster.
Idris Tohidian by his poster.

Poster #4

Investigating thermal stabilization of porcine parvovirus by sugars and amino acids

Authors: Idris Tohidian, Lynn Manchester, Rohan Chaudhari, Dr. Caryn Heldt

Abstract: Developing thermostable vaccines not only reduces vaccination cost, but also increases their widespread distribution all over the world. To achieve this goal, we focused on unravelling the stabilization ability of four sugars and five amino acids frequently used as additives in biotherapeutic formulations today. Both dry and liquid formulations were explored. The results showed good stabilization effect of sugars in liquid and dry formulations, but the amino acids were able to stabilize porcine parvovirus only in the dry state.

Grace Dykstra by her poster.
Presenter Grace Dykstra by her poster.

Poster #5: Second Place Graduate Research

Low-cost, Stable, and Selective Synthetic biosensors for Lactate Detection

Authors: Grace Dykstra, Dr. Yixin Liu

Abstract: High lactate levels can be a sign of lactic acidosis and is attributed to sepsis and septic shock, cardiac arrest, lung disease, and trauma within the body. Electropolymerized Molecularly Imprinted Polymers (eMIPs) can be used to develop biosensors with a molecularly imprinted cavity as their recognition element, with major advantages of low-cost, quick fabrication, inherent selectivity, and stability. We can further enhance eMIPs with Prussian blue (PB) nanoparticles deposited on the electrode surface as a redox-active species to create label-free biosensors for lactate detection with a one-step detection.

Undergraduate Research

Morgan Redding by her poster.
Presenter Morgan Redding by her poster.

Poster #6: Second Place Undergraduate Research

Scaling Down High-Solids Enzymatic Hydrolysis to Increase Sample Throughput

Authors: Morgan Redding, Mikayla Marshalek, Andrea Senyk, Dr. Rebecca Ong

Abstract: One approach toward biofuel production requires lignocellulosic biomass to undergo high-solids enzymatic hydrolysis to convert cell wall carbohydrates into fermentable sugars. However, our current process suffers from bottlenecks in sample throughput, limiting the types of experiments we can perform. To overcome bottlenecks in solids separation, enzymatic hydrolysis will be scaled down from 32 mL hydrolysate volume to ~4–10 mL volume to allow for higher speed processing in microcentrifuge and avoid time consuming vacuum filtration. The new enzymatic hydrolysis procedure will be coupled with a revised pretreatment and microplate fermentation to enable higher throughput processing and analysis of diverse lignocellulosic feedstocks.

Prajeet Kadam by his poster.
Presenter Prajeet Kadam by his poster.

Poster #7: First Place Undergraduate Research

Quantifying Dielectrophoretic Responses of RAW 264.7 Macrophages: Baseline and LPS Activated Cells

Authors: Prajeet Kadam, Juan Cruz-Moreno, Holly Flores, Nick Peterson, Roger Guillory, Zainab Alshoug, Dr. Adrienne R. Minerick

Abstract: Macrophages are critical effector immune cells that eliminate diseased or damaged cells based on their nascent or activation state (induced via lipopolysaccharide, LPS). Dielectrophoretic (DEP) tools induce cellular charges that probe RAW 264.7 macrophages in baseline and LPS-stimulated states by observing changes in cell morphology and quantifying DEP spectra. This provides insights into cell membrane capacitance, conductivity, and polarizability. A custom-designed microfluidic device precisely controls and monitors the cell during DEP experiments, revealing altered cell morphology, stronger DEP responses at higher voltages, and distinctive responses in LPS-activated macrophages at lower frequencies.

Student Organization

AIChE poster.
AIChE poster.

Poster #8: First Place Student Organization, Presenter Addymae Palecek

The American Institute of Chemical Engineers (AIChE)

Authors: Addymae Palecek, Alicia Hinman, Jeffrey Kennedy, Devin Spencer, Brandon Mitchell-Kiss, Jacqui Foreman, Allison Swanson, Danya Salame, Spencer Kaastra, Dr. Jeana Collins

Abstract: The American Institute of Chemical Engineers (AIChE) develops the engineering students at MTU personally and professionally by offering them the opportunity to meet with industry representatives. This connection allows our members to learn about what they do in their role with the company, what their company does, and grow an authentic friendship. AIChE promotes the sharing of knowledge pertaining to the field of chemical engineering and sustainability. This organization has been involved actively in the community, participating in Make a Difference Day and more. AIChE is a Chem-E-Car sponsor; this is a competition where students design a chemical reaction-driven car and compete with other schools at both regional and national levels.

Kobina Akyea Ofori Represents Michigan Tech for the MINER BOOST Research Program

Ph.D. student Kobina Akyea Ofori (chemical engineering) is currently representing Michigan Tech and the Department of Chemical Engineering during a four-day intense training session in Baltimore, Maryland, as part of the MINER BOOST research program and featuring tons of information and socialization opportunities.

MINER BOOST (Mining Innovations for Negative Emissions Resources – Business Orientation and Origination of Spinouts Training) is organized by the U.S. Department of Energy (DOE), specifically ARPA-E (the Advanced Research Projects Agency–Energy), under Douglas Wicks, the program director for waste-to-energy projects.

The program caters to graduate students, stakeholders and investors, and aims to address the absence of a vibrant mining and mineral processing start-up community. It seeks to:

  1. Create a community of mining and mineral processing innovators by bringing together students and postdocs from academic groups within the MINER program.
  2. Teach participants practical skills related to pitching, networking and company building.
  3. Develop case studies evaluating the commercial potential of current projects students and postdocs are working on within the MINER program.

Ofori expressed his enthusiasm about the journey thus far, stating, “The experience has been incredibly exciting!”

Director Caryn Heldt Gives Us a Peek at the H-STEM

Caryn Heldt (ChE/HRI) was quoted in a WZMQ 19 News story featuring a sneak peek at the new H-STEM Engineering and Health Technologies Complex, which is scheduled for partial opening in the spring 2024 semester.

“Not only can the students see what’s going on but they can kind of get more involved cause they see it. The other really exciting part from a faculty point of view is to have a place where research is being done from a subject basis.”

Director of MTU’s Health Research Insitute Caryn Heldt.

Read more and watch the video at WZMQ 19 News, by Mitchell Rife.

Related

Gilchrist’s U.P. visit spotlights innovation

Natalie Nold Makes an Appearance in the Heldt Lab

Natalie Nold in the Heldt Bioseparations Lab.
Natalie Nold in the Heldt Bioseparations Lab.

Caryn Heldt (ChE/HRI) was quoted and Ph.D. student Natalie Nold (chemical engineering) was pictured by Chemical & Engineering News Magazine in a photo essay featuring images of the laboratories where C&EN readers work and what makes those spaces special to them.

A version of the essay appeared in Volume 101, Issue 32 of the magazine.

Read more and view the gallery in “Scenes from Where Chemists Work” in Chemical & Engineering News Magazine.

Scholarships for Success: Husky Pathways for Academic Wellness and Success

Adrienne Minerick (ChE) is the PI on a project that has received a $2,500,000 research and development grant from the National Science Foundation.

The project is titled “S-STEM: Scholarships for Success: Husky PAWS (Pathways for Academic Wellness and Success).”

Richelle Winkler (SS), Briana Bettin (CS) and Michelle Jarvie-Eggart (EF) are co-PIs on this potential six-year project.

Extract

This project will contribute to the national need for well-educated scientists, mathematicians, engineers, and technicians by supporting the retention and graduation of high-achieving, low-income students with demonstrated financial need at Michigan Technological University.

Michigan Tech is a Science, Technology, Engineering, and Math-focused high-research activity institution with approximately 7000 students, located in the rural upper peninsula of Michigan.

Over its six-year duration, this project will:

  • award four-year scholarships to first-year students
  • award additional finishing scholarships to fourth-year students pursuing an accelerated master’s degree
  • include a summer bridge opportunity
  • create a first-year experience designed to develop self-awareness
  • provide continual career counseling
  • establish alumni mentor connections
  • encourage immersive study abroad
  • provide opportunities for undergraduate research.

Scholarships are targeted to full-time students pursuing bachelor’s degrees and accelerated master’s degrees in applied physics, engineering and computer science.

The overall goal of this project is to increase STEM degree completion of low-income, high-achieving undergraduates with demonstrated financial need.

Read more at the National Science Foundation.

Lei Pan on Battery Minerals and Net-Zero Carbon

Lei Pan in his lab.
Lei Pan

Lei Pan (ChE) was mentioned by Gear Technology in a story about U.S. efforts to develop a  domestic supply chain capacity for electric vehicle (EV) batteries, the manufacturing of which is heavily reliant on critical minerals. Pan is the principal investigator of a $2.5 million research project on carbon storage and extraction of critical minerals from mine tailings at MTU. The research and funding award were the subject of a Michigan Tech News story in January.

The DOE awarded grants to develop rapid carbon mineralization and critical mineral extraction technology to 16 projects nationwide, totaling $39 million. Michigan Tech’s project is the only one in the state of Michigan to receive funding from Mining Innovations for Negative Emissions Resource Recovery (MINER).

Michigan Tech’s project is titled “Energy Reduction and Improved Critical Mineral Recovery from Low-Grade Disseminated Sulfide Deposits and Mine Tailings.” According to principal project investigator Lei Pan, it seeks to permanently and cleanly mineralize and store carbon dioxide. This process should potentially enable the mining industry in Michigan’s Upper Peninsula and Minnesota to achieve net carbon zero while extracting critical minerals from low-grade ores.

This focus on battery minerals has led GM, Ford and Stellantis to partner with a variety of suppliers to support battery production in North America.

Read more at Gear Technology, by Matthew Jaster.

North of 60 Mining News mentioned Michigan Tech’s $2.5 million U.S. Department of Energy ARPA-E MINER award for research on carbon storage and extraction of critical minerals from mine tailings. Lei Pan (ChE) is the project’s principal investigator (PI), and David Shonnard and Tim Eisele (both ChE) are co-PIs. The award was covered by Michigan Tech News in January.

Related

Michigan Tech Awarded $2.5 Million to Unlock Net-Zero Emission Mineral Extraction Technologies in Mining Industries

Heldt Group Attending ACS Fall 2023

Researchers in the Heldt Bioseparations Lab will be attending the ACS fall meeting on August 13–18.

Caryn Heldt – “Empty and full AAV capsid charge and hydrophobicity differences measured with single particle AFM”

Caryn Heldt is the James and Lorna Mack Chair in Bioengineering in the Department of Chemical Engineering.

Caryn Heldt – “Virus encapsulation in polypeptide complexes for thermal stable vaccine formulations”

Caryn Heldt – “Expanding the diversity, equity, inclusion, and sense of belonging of graduate students at Michigan Tech”

Vaishali Sharma – “Mechanistic understanding of eco-friendly surfactants for virus inactivation”

Vaishali Sharma is a PhD student in biological sciences.

Seth Kriz – “Scaling down to scale up: Mass transport of viruses in aqueous two-phase systems”

Seth Kriz is a PhD student.

Natalie Nold – “Economics and process monitoring of continuous vaccine production using aqueous two-phase systems”

Natalie Nold is a PhD student.

The meeting will be held in San Francisco with a hybrid format. The 2023 meeting title is Harnessing the Power of Data.

ACS Meetings and Expositions are where chemistry professionals meet to share ideas and advance scientific and technical knowledge.

The Heldt Bioseparations Lab focuses on the science of viral surface interactions and applies it to vaccine manufacturing and purification.

Podcast: Systems of Support with Rebecca Ong

The Great Lakes Bioenergy Research Center (GLBRC) is releasing the second season of Propelling Women in Power, one episode of which features Rebecca Ong, Director of Graduate Programs and Associate Professor of Chemical Engineering at Michigan Technological University. Propelling Women in Power is a podcast about the careers of women in energy at the Wisconsin Energy Institute on the UW–Madison campus and our sister institution, the Great Lakes Bioenergy Research Center.

In this episode, Becky Ong (ChE) shares her journey from her childhood love of plants to her groundbreaking research in converting them into biofuels. Listen in for insights on how academia can better support and empower women in STEM and how access to STEM education and representation should start in early childhood.

S2, Ep. 3 Listen (41:29)

Chemical Engineering Inducts Six into Distinguished Academy

Two people standing at the social ceremony.
Dean Janet Callahan and Bruce Janda at the academy social.

The department of Chemical Engineering inducted six alumni into our Distinguished Academy on Friday April 14th, 2023, at the Miscowaubik Club in Calumet.

The purpose of the Academy is to honor outstanding graduates of the Michigan Technological University Department of Chemical Engineering. Selection into the Academy recognizes excellence and leadership in engineering and civic affairs.

This induction honors some of the most successful alumni of Michigan Tech’s Department of Chemical Engineering. Portraits and a brief biography of Academy members are prominently displayed on the Distinguished Academy Honor Wall in the hallway outside the main departmental offices to serve as inspirational role models for future Chemical Engineering students.

The 2023 Inductees include Bryan Glover ’86, Bruce Janda ’76, Carlos Jorda ’71, Brad Rick ’84, ’86, John Smuk ’55, Phillip Watters ’69.

Bryan Glover is President and CEO of Honeywell UOP, a Des Plaines, IL based company, which is the leading provider of technologies for the global energy and petrochemicals industries. Since 1914 UOP has led the development of technologies for oil refining, petrochemicals, natural gas processing and most recently a full range of sustainable technologies including renewable fuels, clean hydrogen, carbon capture, energy storage and advanced plastics recycling.

Bruce W. Janda recently retired as Senior Consultant at Fisher International. He is a TAPPI Fellow and Education Committee Chair of TAPPI’s Tissue Division. He is also a tissue paper product and process expert, serving as the leader of TAPPI’s Tissue 101, 202, and 203 courses. Bruce continues to write and consult on the tissue business and technology as InnovaSpec, LLC.

With 52 years of experience in the international oil and gas industry, Carlos Jordá has served at the highest executive levels in refining and marketing, corporate planning, finance, and the production of Syncrude from Venezuela’s Orinoco Belt with PDVSA, rising to President of PDV America and Chairman of the CITGO Board of Directors.

Brad Rick graduated from MTU with degrees in Chemical Engineering (BSChE 1984, MSChE 1986). He spent his 35 year career with Amway Corporation in Ada, Michigan, beginning as a Process Engineer developing and scaling processes for personal care and cosmetic products. Brad transitioned to Product Development leading engineering and design efforts for a small appliance division where he received four US patents and multiple foreign patents for the design of an air treatment system.

A native of Aurora, MN, John Smuk attended St. Thomas College in St. Paul for two years prior to transferring to Michigan Tech to play football and complete his B.S. degree with honors in Chemical Engineering. He was initiated into the Phi Lambda Upsilon honorary chemical engineering and Sigma Xi. John passed away on April 2, 2022, at the age of 90.

Philip Watters received a B.S. in chemical engineering from Michigan Tech in 1969 and then joined the Exxon Chemical Company. During his years at Exxon, Philip earned an MBA from the University of Houston in 1972. Philip has spent his career working on various aspects of the business in the field of petrochemical and energy industry. In 1986, he joined Resource Planning Consultants first as Vice-President and then as President. Philip joined Rimkus Consulting Group in 1989 and served as Senior Vice President for 30 years.

View the Photo Gallery

Related

CITGO CEO Carlos Jordá Among Six Alumni Honored by Michigan Tech

“I was honored to receive this recognition from my alma mater, Michigan Tech. My background in chemical engineering has proven highly valuable throughout my career in the international oil and gas industry, and I’m proud to join the academy alongside such a distinguished group of fellow inductees.”

Carlos Jordá, CITGO CEO