Category: Research

Werner, X. Tang, featured in Michigan Tech Lode

Dr. Thomas Werner and Dr. Xiaoqing Tang are featured in two separate articles in the last couple of week in the Michigan Tech Lode.

The article on Dr. Werner’s research titled “Inside Look: Fruit Flies, Color Patterns and Cancer” can be found in the 8 October 2015 issue.

The article on Dr. Tang’s research titled: “Solving the mystery: what connects microRNA and proteins to the pancreas” can be found in the 1 October 2016 issue.


Updated: Biology students do well in LSTI 1st Annual Research Forum

The First Annual Research Forum sponsored by the Life Science and Technology Institute was held Sept. 24 and 25. Twenty-seven graduate and undergraduate students conducting research in life science, biotechnology, human health and related areas presented posters.

Thank you to participants, the judges and all who helped with the successful forum. A list of LSTI award winners is as follows:

Graduate Grand Prize

Sanaz Habibi (ChE) “Do Faradaic Reactions cause Hemolysis in Non-Uniform Alternating Current Electric Fields,” Advisor: Minerick

Graduate Merit Awards

  • Ramkumar Mohan (Biology)—”MicroRNA-483, A Differentially Expressed MicroRNA Between Pancreatic Beta Cells and Alpha Cells,” Advisor: Zhang/Tang
  • Ni Fan (Chem)—”Glycan-Dependent Mutual and Reversible Sequestration,” Advisor: Dam
  • Robert Larson (KIP)—”High Salt Intake Augments Excitability of Pre-sympathetic PVN Neurons,” Advisor: Chen

Undergraduate Grand Prize

Jared Pecore (Biology)—”The Mechanisms Underlying α-Amanitin Resistance in Drosophila melanogaster: A Microarray Analysis,” Advisor: Werner

Undergraduate Merit Award

Dakota Anderson (KIP)—”Upper-Extremity Eccentric Exercise: Increases in Muscle Strength and Power at Moderate Training Intensities” 

UPDATED: Here is a photo gallery of  participants.

Taken from Tech Today


UPDATED: Solving the Mystery That Connects MicroRNA and Proteins in the Pancreas

Dr Tang’s research is featured this week on Michigan Tech’s home page.    

By Allison Mills MicroRNA strands were once thought of as junk genetic material. Now, researchers know that these small structures help program surrounding genes, affecting everything from eye color to cancer. For diabetes, one such connection is a classic whodunit—it was miR-483 with the SOCS3 protein in the pancreas. Unraveling this mystery is the subject of a new paper published in the Journal of Biological Chemistry.

Pancreatic Cells

Xiaoqing Tang, one of the study co-authors and an assistant professor of biology at Michigan Technological University, is poised. She is as calm as you’d expect a sleuth to be, and she explains the complex interactions of pancreatic microRNA with the meticulousness of a crime scene investigator.

First, Tang says, we have to start with the big picture—the pancreatic cells where these genes interact.

“We’re interested in the alpha and beta cells,” says Tang, explaining that beta cells secrete insulin and alpha cells secrete glucagon, which regulate our blood sugar levels. A normal ratio is generally 80 percent beta cells and 15 percent alpha cells. “In type 2 diabetic patients, the ratio is imbalanced and we see beta cell loss and alpha cell expansion,” the researcher says.

Balancing these hormones is difficult to coordinate because several organs—the liver and brain as well as the pancreas—are involved. But the real nuance is within the alpha and beta cells themselves.

More at the University News site


New Funding – Huckins Co-PI

Joseph Wagenbrenner (SFRES/GLRC), is the principal investigator on the project Informing Great Lakes Connectivity Decisions: An Enhanced Online Portal for High-Resolution Barrier Data and Species-Specific Benefit Analysis, that has received a $42,105 research and development grant from the University of Wisconsin. Casey Huckins (Bio Sci) and David Watkins (CEE) are co-PIs on the two-year project.


Updated: Durocher and colleagues publish two papers

Congratulations to Dr. John Durocher and colleagues on their new publication:
 Recent PhD graduate Erich Petushek (CLS; MSU College of Human Medicine), Associate Professor Edward Cokely (CLS), Assistant Professor John Durocher (Bio Sci), Paul Ward (University of Huddersfield, UK), Sean Wallace (Illinois Institute of Technology), and Gregory Myer (Cincinnati Children’s Hospital Medical Center) published the paper “Injury Risk Estimation Expertise: Assessing the ACL Injury Risk Estimation Quiz,” in The American Journal of Sports Medicine, 2015 43: 1640-1647. The Am J Sports Med is currently ranked 2 of 72 for Orthopedics and 3 of 81 for Sports Sciences based on Impact Factor. Here is a link to the article:http://ajs.sagepub.com/content/43/7/1640.full.pdf+html?sid=51b1fdd9-109c-4b1b-8346-5840921ed2a3
Assistant Professor John Durocher (Bio Sci), Professor Jason Carter (KIP), William Cooke (University of Texas at San Antonio), Angelea Young (Bio Sci & KIP), and Morton Harwood (Bio Sci) published a paper “Cerebral Blood Flow Velocity During Combined Lower Body Negative Pressure and Cognitive Stress,” in Aerospace Medicine and Human Performance, Volume 86, Number 8, August 2015, pp. 688-692. Here is a link to the article abstract: http://michigantechmi.library.ingentaconnect.com/content/asma/amhp/2015/00000086/00000008/art00003