Graduate School Newsblog

Tag: Chemistry

New theses and dissertations in the Library

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The Graduate School is pleased to announce the arrival of new theses and dissertations from our recent graduates in the J. R. Van Pelt Library and John and Ruanne Opie Library.  The names of our graduates, their degrees, advisors, and titles of their research are listed below.

Manoranjan Acharya
Doctor of Philosophy in Electrical Engineering
Advisor: Paul L Bergstrom
Dissertation title: Development of Room Temperature Operating Single Electron Transistor using FIB Etching and Deposition Technology

Susan H Balint
Master of Science in Environmental Policy
Advisor: Kathleen E Halvorsen
Thesis title: Federal and State Policy Influence on Woody Biomass Utilization

Genevieve M Borg
Master of Science in Environmental Policy
Advisor: Carol A MacLennan
Thesis title: EPA’s Council for Regulatory Environmental Modeling: A Case Study of Science Policy Implementation

Carmelo Davila
Master of Science in Industrial Archeology
Advisor: Samuel R Sweitz
Thesis title: A Space for Production and a Space for Communality: Socio-Historical Study of Central Aguirre and its Industrial Community, Salinas, Puerto Rico: 1949-1970

Seth C DePasqual
Master of Science in Industrial Archeology
Advisor: Patrick E Martin
Thesis title: Winning Coal at 78 Degrees North: Mining, Contingency and the Chaine Operatoire in Old Longyear City

Robert S Donofrio
Doctor of Philosophy in Biological Sciences
Advisor: Susan T Bagley
Dissertation title: Development and Validation of Selective and Differential Enumeration Methods for Brevundimonas diminuta

Jason T Dreyer
Doctor of Philosophy in Mechanical Engineering – Engineering Mechanics
Co-advisors: Sudhakar M Pandit and Mohan D Rao
Dissertation title: Binaural Index for Speech Intelligibility via Bivariate Autoregressive Models

Ingrid D Fedde
Master of Science in Geology
Co-advisors: Jose Luis Palma Lizana and William I Rose
Thesis title: Application of Probabilistic Tools and Expert Elicitation for Hazard Assessment at Volcan de Colima, Mexico

Travis J Hansen
Master of Science in Chemical Engineering
Advisor: Daniel A Crowl
Thesis title: Estimation of the Flammability Zone Boundaries with Thermodynamic and Empirical Equations

Daniel E Haskell
Master of Science in Applied Ecology
Advisor: David J Flaspohler
Thesis title: `Restoration in Northern Wisconsin

Stacie A Holmes
Doctor of Philosophy in Forest Science
Advisor: Christopher R Webster
Dissertation title: The Influence of Concurrent Disturbances on Plant Community Dynamics in Northern Hemlock-Hardwood Forests

Ashwini S Kashelikar
Master of Science in Environmental Engineering
Advisor: Veronica W Griffis
Thesis title: Identification of Teleconnections and Improved Flood Risk Forecasts using Bulletin 17B

Justin D Keske
Doctor of Philosophy in Mechanical Engineering – Engineering Mechanics
Advisor: Jason R Blough
Dissertation title: Investigation of a Semi-Active Muffler System with Implementation on a Snowmobile

Paul J Koll
Master of Science in Forest Ecology and Management
Advisor: Martin F Jurgensen
Thesis title: Effects of Conifer Sawdust, Hardwood Sawdust, and Peat on Soil Properties and Bareroot Conifer Seedling Development

Andrew T Kozich
Master of Science in Environmental Policy
Advisor: Kathleen E Halvorsen
Thesis title: Wetland Mitigation in Michigan’s Upper Peninsula: Compliance with Site Monitoring and Invasive Plant Species Standards

Kateryna Lapina
Doctor of Philosophy in Environmental Engineering
Co-advisors: Richard E Honrath and Judith A Perlinger
Dissertation title: Boreal Forest Fire Impacts on Lower Troposphere CO and Ozone Levels at the Regional to Hemispheric Scales

Joseph W Lechnyr
Master of Science in Mechanical Engineering
Advisor: Jeffrey Allen
Thesis title: Imaging of Fuel Cell Diffusion Media Under Compressive Strain

Angela K Lucas
Master of Science in Biological Sciences
Advisor: Jason R Carter
Thesis title: Effects of Pediatric Adiposity on Heart Rate Variability

Lawrence J Mailloux
Master of Science in Chemistry
Advisor: Dallas K Bates
Thesis title: A 1,2,4-Triazole to Thiazole Transformation

Meghan E McGee-Lawrence
Doctor of Philosophy in Biomedical Engineering
Advisor: Seth W Donahue
Dissertation title: Skeletal Preservation by Hibernating Bears

Diane M Miller
Doctor of Philosophy in Rhetoric and Technical Communication
Advisor: Patricia J Sotirin
Dissertation title: Speaking (of) Community: An Ethnographic Study of the Relationships Among Communication, Community, and Everyday Experience at an Organic Foods Cooperative

Min Nie
Master of Science in Mechanical Engineering
Advisor: Desheng Meng
Thesis title: Fabrication of Nanoparticles by Short-Distance Sputter Deposition

Brian A Ott
Doctor of Philosophy in Chemical Engineering
Advisor: Gerard T Caneba
Dissertation title: Fluid Phase Equilibrium as Modeled by the Statistical Associated Fluid Theory (SAFT) Equation of State

Robert C Owen
Doctor of Philosophy in Environmental Engineering
Advisor: Richard E Honrath
Dissertation title: Long-range Pollution Transport: Trans-Atlantic Mechanisms and Lagrangian Modeling Methods

Jeannie A Patrick
Doctor of Philosophy in Rhetoric and Technical Communication
Advisor: Diane L Shoos
Dissertation title: Not Your Mother’s Latinas: Film Representations for a New Millennium

David M Pauken
Master of Science in Mechanical Engineering
Advisor: John W Sutherland
Thesis title: Statistical Modeling of the Ford Superduty Brake Pedal Feel Attribute

Melissa J Porter
Master of Science in Forest Ecology and Management
Advisor: Andrew J Storer
Thesis title: Detection and Landing Behavior of Emerald Ash Borer, Agrilus planipennis, at Low Population Density

Mark D Rowe
Master of Science in Environmental Engineering
Advisor: Judith A Perlinger
Thesis title: Modeling Contaminant Behavior in Lake Superior: A Comparison of PCBs, PBDEs, and Mercury

Ryan W Schweitzer
Master of Science in Environmental Engineering
Advisor: James R Mihelcic
Thesis title: Community Managed Rural Water Supply Systems in the Dominican Republic: Assessment of Sustainability of Systems Built by the National Institute of Potable Water and Peace

Xiaoning Shan
Doctor of Philosophy in Electrical Engineering
Advisor: Jeffrey B Burl
Dissertation title: Time-Varying System Identification in the Transform Domain

Sarah E Stehn
Master of Science in Forest Ecology and Management
Advisor: Christopher R Webster
Thesis title: Influence of Exogenous Disturbance on Bryophyte Community Assemblage and Tree Regeneration Dynamics in Southern Appalachian Spruce-Fir Forests

Xiang Sun
Doctor of Philosophy in Materials Science and Engineering
Advisor: Jiann-Yang Hwang
Dissertation title: Charge Induced Enhancement of Adsorption for Hydrogen Storage Materials

Iltesham Z Syed
Master of Science in Mechanical Engineering
Advisor: Abhijit Mukherjee
Thesis title: Experimental Study of Forced Convection Heat Transfer to Water Flowing through a Short Micro Duct at the Tip of a Cutting Tool at Turbulent Reynolds Number

Jacob T Vermillion
Master of Science in Civil Engineering
Advisor: Lawrence L Sutter
Thesis title: Absorption Correction for the Determination of the Water Content of Fresh Concrete Using the Microwave-Oven Drying Method

Dennis K Walikainen
Doctor of Philosophy in Rhetoric and Technical Communication
Advisor: Robert R Johnson
Dissertation title: What’s It Like There? Toward a Rhetoric of University Maps and Tours

Cheryl L Williams
Master of Science in Mechanical Engineering
Advisor: John W Sutherland
Thesis title: Optimization of Conversion of North American Left Hand Drive Vehicles for Importation into Right Hand Markets

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Beautiful Bugs in Blue: The Making of Luminous Bacteria

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Published in Tech Today

by Marcia Goodrich, senior writer

A team of Michigan Tech researchers led by Associate Professor of Chemistry Haiying Liu has discovered how to make a strain of E. coli glow under fluorescent light. The technique could eventually be used to track down all sorts of pathogens and even help in the fight against breast cancer.

E. coli bacteria are naturally found in animal intestines and are usually harmless. But when virulent strains contaminate food, like spinach or peanuts, they can cause serious illness and even death.

The researchers’ trick takes advantage of E. coli’s affinity for the sugar mannose. Liu’s team attached mannose molecules to specially engineered fluorescent polymers and stirred them into a container of water swimming with E. coli. Microscopic hairs on the bacteria, called pili, hooked onto the mannose molecules like Velcro, effectively coating the bacteria with the polymers.

Then the researchers shined white light onto E. coli colonies growing in the solution. The bugs lit up like blue fireflies. “They became very colorful and easy to see under a microscope,” said Liu.

The technique could be adapted to identify a wide array of pathogens by mixing and matching from a library of different sugars and polymers that fluoresce different colors under different frequencies of light. If blue means E. coli, fuchsia could one day mean influenza.

With funding from a Small Business Innovation Research grant from the National Institutes of Health, Liu is adapting the technique to combat breast cancer. Instead of mannose, he plans to link the fluorescent polymers to a peptide that homes in on cancer cells.

Once introduced to the vascular system, the polymers would travel through the body and stick to tumor cells. Then, illuminated by a type of infrared light that shines through human tissue, the polymers would glow, providing a beacon to pinpoint the location of the malignant cells.

The technique would allow surgeons to easily identify and remove malignant cells while minimizing damage to healthy tissue.

The team’s work using polymers to detect E. coli was partially supported by the US Department of Agriculture and has been published in Chemistry–A European Journal.

The article, “Highly Water-Soluble Fluorescent Conjugated Fluorene-Based Glycopolymers with Poly(ethylene glycol) Tethered Spacers for Sensitive Detection of Escherichia coli,” is coauthored by Liu, postdoctoral associate Cuihua Xue, graduate students Singaravelu Velayudham and Steve Johnson, undergraduates Adrian Smith and Wilbel Brewer and Professor Pushpalatha Murthy, all of Michigan Tech’s chemistry department; and graduate student Ratul Saha and Professor Susan T. Bagley of the biological sciences department.

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