Weihua Zhou, assistant professor, Health Informatics, and member of the ICC’s Center for Data Sciences, is the principal investigator on a project that has received a $24,497 federal pass-through research and development grant from Tulane University. The project is titled, “Trans-Omics Integration of Multi-Omics Studies for Male Osteoporosis.” This is a 7-1/2 month project.
Abstract: Osteoporosis is the most prevalent metabolic bone disease and it is representative of many diseases typical of aging. While advances in omics technologies, such as genomics, transcriptomics, proteomics, and epigenomics, have been successful in identifying risk loci for osteoporosis, each technology individually cannot capture the entire biological complexity of osteoporosis. The integration of multiple technologies has emerged as an approach to provide a more comprehensive view of biology and disease. In addition, recent advances in image analysis have enabled the characterization of not only the bone mineral density but also the bone microarchitecture and biomechanical quality with the dual-energy x-ray absorptiometry (DEXA) and quantitative computed tomography (QCT) measurements. The Tulane Center for Bioinformatics and Genomics (CBG), led by Dr. Hong-Wen Deng, has accumulated/is acquiring extensive multi-omics data and DEXA/QCT images through a number of research projects for osteoporosis and other related phenotypes. Tulane CBG is actively seeking collaborations with investigators who have the expertise and experience in integrative multi-omics analysis and advanced image analysis. With this NIH subcontract award (U19AG055373), Tulane CBG will collaborate with Dr. Weihua Zhou and his team on the development and implementation of sophisticated methods for multi-omics analysis and DEXA/QCT image analysis.
Dr. Zhou is looking for volunteer research assistants. Please visit his web pages for more details: https://pages.mtu.edu/~whzhou/, and read this blog post: https://blogs.mtu.edu/computing/2019/12/03/medical-imaging-…earch-assistants/.