Category: Research

KIP Students Tie for Third Place in Poster Competition at 2023 Upper Peninsula Medical Conference

From left to right: Lexi Little, Lily Hart, Gracie VanLangevelde, Dr. Carolyn Duncan at UP Medical Conference held at MTU on October 28, 2023.

The research group that works in Dr. Carolyn Duncan’s Biomechanics Lab tied for 3rd place in the student poster competition. “My personal highlight of the conference was seeing the students interact with the healthcare professionals. The networking experience was awesome, and they seemed so excited that the work they were doing was of interest to people in the profession,” remarked Dr. Duncan. Learn more about the students’ research and work in the abstract below.

Utilizing Surface Electromyography and Kinematic Analyses to Quantify Deep Tendon Reflexes

Alexandra Little (BioSci), Gracie VanLangevelde (KIP), Lily Hart (KIP), Cameron Williams (CMU), Todd Hall (KIP), Carolyn Duncan (KIP)

Michigan Technological University, Central Michigan University

Deep tendon reflexes (DTRs) are a fundamental part of neurological examinations. Clinical observations and past studies have suggested that abnormal DTRs are a sign of corticospinal tract abnormalities or dysfunction with other descending pathways that influence the reflex arc. However, there are challenges regarding the interpretation and understanding of reflex excitability in clinical settings. There have been some attempts at using alternative methods, such as electromyography, to mechanically quantify DTRs for interpretation. However, this research has been limited to smaller focused studies and has not been used to examine and characterize DTRs across larger populations.

The overarching goal of the research is to characterize and quantify DTR responses using surface EMG and kinematic analyses. To accomplish this, our research team is currently performing 2 studies that aim to 1) Quantifying and determining the repeatability of DTR in healthy varsity athletes 2) Evaluating the relationship between neuromuscular output and DTR rating and 3) Examining the influence of concussions and contact sports on DTR response. In all studies surface EMG electrodes and inertial measurement units (IMU) are utilized to help quantify responses during standard quadriceps, achilles, biceps and triceps DTR testing. While this research is currently ongoing, initial findings suggest that surface electromyography and kinematic analyses can provide more precise information about DTR responses. Moving forward, these initial findings provide the foundational basis for future research examining DTR responses. This research also demonstrates the potential for utilizing EMG and kinematic analyses in clinical settings to gain more information about DTR responses.

KIP Presents Research at Midwest American College of Sports Medicine Annual Conference

Kyle Wehmanen and Dr. Steven Elmer from the Department of Kinesiology and Integrative Physiology traveled to Indianapolis, Indiana for the Midwest American College of Sports Medicine (ACSM) Annual Conference held on October 12-14, 2023. The conference brought together over 400 students, faculty, and professionals focused on kinesiology and sports medicine from across the Midwest states, including Michigan, Ohio, Indiana, Illinois, and Wisconsin.

This year was the 50th Midwest ACSM Annual Conference, which included a keynote presentation on “The Learning Connection: how physical activity, nutrition, free play and nurturing grow a healthy kid” by Anastasia Fischer, MD from Nationwide Children’s Hospital and The Ohio State University College. There were also 18 faculty and professional-led symposia, over 100 student oral and poster presentations, professional development sessions, and networking opportunities. To celebrate the Midwest chapter’s 50th anniversary, there was a historical presentation that highlighted how the chapter was started and how it has grown over the years to become what it is today.

Kyle Wehmanen, “Metabolic Cost Of Human Locomotion On Soft Terrain”
Dr. Steve Elmer (pictured on right), “Single-leg Cycling for Improving Performance, Restoring Function, and Facilitating Research”

Kyle Wehmanen, a second-year PhD student, presented a poster highlighting his research conducted in the Exercise Physiology Laboratory titled “Metabolic Cost of Human Locomotion on Soft Terrain.”

“Attending and presenting the MWACSM conference is a highlight for me every year. It always provides an inviting environment to share your research while gaining valuable feedback. It also provides a great opportunity to meet new like-minded individuals and have personal conversations with esteemed researchers in your areas of interest,” said Wehmanen.

Dr. Elmer presented as part of symposium that focused on “Single-Leg Cycling for Improving Performance, Restoring Function, and Facilitating Research” on day one of the conference and on “Science Communication and Advocacy: Current Topics and Integration with Your Career” on day two. The questions and feedback that Wehmanen and Elmer received will strengthen their projects and move their work forward. Overall, it was an excellent conference and professional development opportunity. A special thank you to the Michigan Space Grant Consortium and American Physiological Society for supporting the research and scholarly work that was presented by Wehmanen and Elmer. Also, thank you to members of the Exercise Physiology Laboratory and the Department of Kinesiology and Integrative Physiology for their continued support.

KIP Faculty Featured at MTU-MSU Symposium on Michigan Tech’s Campus

On Friday, October 27, 2023, Dr. Steve Elmer, Dr. William Cooke, and Dr. Jenny Shan from the KIP department presented at the Engineering The Future of Human Health II: Collaborative Research Symposium held on the MTU campus in the Memorial Union Building. This is the second symposium being held in conjunction with Michigan State University. The inaugural symposium was held at MSU in March of 2022. Michigan Tech hosted this symposium with Dr. Cooke as a co-sponsor. “This is an important collaborative opportunity,” he commented.

Dr. Elmer and Dr. Cooke presented in the “Kinesiology and Physiology” session, and Dr. Shan presented in the “Metabolic Disease” session. Dr. Cooke also served as a moderator for the “Neural Control and Disease” session.

The symposium made the local TV6 news. More information and highlights about the event can be found on the station’s website.

Dr. Steve Elmer’s presentation, “Beyond the Weight Room: The Importance of Exercise in Health and Disease”
Dr. William Cooke’s presentation, “Inspiratory Resistance and Hemorrhage Control”
Dr. Jenny Shan’s presentation, “Exploring the Involvement of Extracellular Vesicles in Regulating Blood Pressure”

KIP Students Stay Active During Summer Break Presenting at National ACSM Annual Meeting

Isaac Lennox presents his research on the impact of “Exercise is Medicine-On Campus” at ACSM.
Kyle Wehmanen talks during a group session about his analysis of long-distance winter ultra-endurance racing.

The American College of Sports Medicine (ACSM) Annual Meeting took place May 30-June 2, 2023 in Denver, Colorado.

In attendance were two KIP graduate students, Isaac Lennox (MS) and Kyle Wehmanen (PhD), along with recent PhD graduate Isaac Wedig. All three attendees were proud to present their recent research at the ACSM conference.

Isaac Lennox presented a poster from his master’s research focusing on the nationwide impact of the “Exercise is Medicine-On Campus” (EIM-OC) initiative. EIM-OC is a program run by the ACSM that promotes physical activity on college campuses and is a pillar of their continuing community outreach. Isaac L.’s work was very well received and garnered excitement and interest from other EIM-OC colleagues across the country.

Isaac Wedig gave a short, rapid-fire oral presentation on a portion of his doctoral research. He outlined his work with blood flow restriction (BFR) and exercise. Specifically, Isaac W. has built tools designed to help bridge the gap with BFR between research and practical usage in a clinical setting.

Finally, Kyle Wehmanen delivered a 10-minute talk as part of a group session on endurance athletes and events. He spoke about his ongoing analysis of long-distance winter ultra-endurance racing, including the 1000-mile Iditarod Trail Invitational which traverses the same course as the legendary dog-sled race.

Overall, the Michigan Tech crew had a fantastic showing at the 2023 ACSM Annual Meeting and are already looking forward to next year! — Written by Kyle Wehmanen, PhD student

KIP Students Present at 2023 American Physiology Summit

Students and faculty from the Department of Kinesiology and Integrative Physiology (KIP) recently attended the 2023 American Physiology Summit in Long Beach, CA on April 20–23, 2023. PhD students Greg Miodonski, Sherry Chen, Kyle Wehmanen, and Isaac Wedig presented posters to their colleagues at the annual event.

Greg, a member of Dr. Qinghui Chen’s lab, did a poster presentation of his research project entitled “Exercise Augments Small Conductance Ca2+ -Activated Potassium Channel (SK) Function in the PVN of Sprague Dawley Rats to Reduce Sympathetic Outflow.” His poster was selected as “top 10% scoring abstracts” sponsored by APS Central Nervous Session (CNS). Read more about his research in his abstract below.

Congratulations to these students for a wonderful showing at the summit!

Greg Miodonski, Qinghui Chen, and Mingjun Gu at APS
Top row from left to right: Qinghui Chen (KIP faculty), Gregory Miodonski (KIP student); Ian Greenlund (KIP alum); Jeremy Bigalke (KIP alum), Robert Larson (BioSci faculty); John Durocher (former KIP faculty)
Bottom row from left to right: Mingjun Gu (KIP researcher), Sherry Chen (KIP student), Jennifer Nicevski (KIP alum), Jenny Shan (KIP faculty)

Greg’s Abstract:

“Exercise Augments Small Conductance Ca2+ -Activated Potassium Channel (SK) Function in the PVN of Sprague Dawley Rats to Reduce Sympathetic Outflow”

Gregory Miodonski, Jessica Bruning, Derrick Simet, Haley Ruiter, Christian Johnson, Mingjun Gu, Zhiying Shan, Qing-Hui Chen

Elevated sympathetic outflow is a key feature of cardiovascular disease (CVD) that worsens disease progression. Our lab has shown that SK channels expressed in the PVN play a crucial role in regulating neuronal activity and sympathetic outflow, and that SK channels become dysfunctional in rats fed a high salt diet. Exercise has been shown to be an effective treatment for reducing sympathoexcitation in CVD including hypertension and heart failure, but the underlying mechanisms are not fully understood. We hypothesized that aerobic exercise would upregulate SK channel function in the PVN to reduce sympathetic nerve activity (SNA). To test this, 5–6 week old Sprague Dawley rats were randomly divided into sedentary (SED) and exercise (EXT) two groups and fed a 0.4% NaCl normal salt diet. Following acclimation, EXT groups ran on a motorized treadmill 5 days/week for 8-10 weeks. Conscious blood pressure was measured weekly via tail plethysmography. After 8-10 weeks, animals were anesthetized and underwent in vivo surgery to record the renal sympathetic nerve activity (RSNA) and mean arterial pressure (MAP) following PVN microinjection of the SK blocker, apamin (0.25mM, 60nL/side). The data showed that the RSNA response to PVN apamin was significantly enhanced in EXT rats compared with SED rats (320.8 ± 174.6 % baseline, n=9 vs 184.8 ± 143.1 % baseline, n=9; p = 0.02).  The corresponding ABP response to apamin was not significantly different in EXT rats compared with SED rats (20.40 ± 9.98 mmHg, n=9 vs 25.27 ± 9.97 mmHg, n=8; p = 0.1658). Our data indicates exercise enhances PVN SK channel function to reduce sympathetic outflow. This improvement of SK channel function may be one mechanism by which exercise reduces SNA in CVD including hypertension and heart failure. Support: 1R15HL145655 (Chen); 1R15 HL150703 (Shan); MTU Health Research Institute (HRI).

Greg Miodonski, PhD student
Kyle Wehmanen, PhD student, presented his project entitled “Teaching K-12 Students Using Jenga: The Impact of Health Behaviors on Community Health, Wellbeing, and Resilience.”
Not pictured, PhD student Isaac Wedig presented his research project entitled “”Predictors of Arterial Occlusion Pressure in the Lower-Body Across Commonly Used Cuff Widths.”
PhD student Sherry Chen’s research project is entitled “Brain-Derived Small Extracellular Vesicles from Dahl Salt-Sensitive Rats with High Salt Diet Induce Inflammation and Oxidative Stress.”
Sherry Chen with Dr. Jenny Shan

Call for Applications: 2023 Songer Research Award for Human Health

Undergraduate and graduate students in the Kinesiology and Integrative Physiology Department are encouraged to apply for the 2023 Songer Research Award for Human Health. Matthew Songer, (Biological Sciences ’79) and Laura Songer (Biological Sciences ’80) established these awards to stimulate and encourage opportunities for original research by current Michigan Tech students.

Students may propose an innovative medically-oriented research project in any area of human health. The best projects will demonstrate the potential to have a broad impact on improving human life. This research will be pursued in consultation with faculty members within the College of Sciences and Arts. The Songers’ gift and matching funds from the College will support two awards for undergraduate research ($4,000) and two for graduate research ($6,000), for research conducted over the Summer of 2023 and/or the following academic year.

Learn more about who is eligible to apply, how to apply, and how the funds may be used.

Submit applications as a single PDF file to the Office of the College of Sciences and Arts by 4:00 p.m. Monday, April 24, 2023. Applications may be emailed to djhemmer@mtu.edu. Any questions may be directed to David Hemmer (djhemmer@mtu.edu).

PhD Student Receives Award at the 2023 National Safe Patient Handling and Mobility Education Event

Ashley Hawke, PhD student

PhD student Ashley Hawke received the Gallagher Award at the 2023 National Safe Patient Handling and Mobility Education Event that took place in Glendale, AZ from March 20-23, 2023. This national event is hosted by the Association of Safe Patient Handling Professionals.

The award Ashley received is for her project proposal entitled “Effectiveness of Patient Handling Interventions on Reducing Musculoskeletal Disorder Risk in Healthcare Workers: A Study Proposal.” Below is her project’s abstract to learn more about Ashley’s work.

Background: Musculoskeletal disorders (MSDs) are extremely prevalent among healthcare workers, especially those who perform patient handling tasks. Previous research has found that sustained static and/or awkward working postures, frequent bending, repetitive and/or forceful work, and twisting were commonly associated with MSDs. The use of mechanical assistive devices reduces risks of MSDs during patient handling; however, availability and accessibility of equipment are common barriers to using these devices in clinical settings. Portable passive interventions, such as transfer slings, slider sheets, and exoskeletons have been proposed to assist with patient handling tasks as an alternative to mechanical assistive devices, but the effectiveness of these interventions in reducing MSD risk in healthcare workers is inconclusive. METHODS: In the proposed study, we will evaluate three passive patient handling interventions (transfer sling, slider sheet, and passive back-assist exoskeleton) in their ability to alter biomechanical and physiological responses associated with the development of MSDs when performing two standardized patient handling tasks: 1) turning a patient onto their side and 2) performing a sit to sit transfer. Twenty participants will be recruited to perform the tasks using an 80 kg mannequin in four different interventions: manual, using a transfer sling, using a slider sheet, and wearing a passive exoskeleton. Variables to be measured include muscle activity of the trunk, upper extremity, lower extremity muscles, shoulder/lumbar kinematics, kinetics, oxygen consumption, heart rate, energy expenditure, and rating of perceived exertion. FINDINGS: As this is a study proposal, no results are available at this time. CONCLUSIONS/IMPLICATIONS: Results from the proposed study will allow researchers to evaluate the biomechanical demands and physiological cost of each patient handling intervention and how together these may play a role in potentially reducing MSDs. Importantly, these findings may serve as a first step to developing more cost-effective and portable patient handling interventions.

KIP Alum Wins AJP 2023 Best Research Article Award

KIP alum Joshua Gonzalez (PhD, Integrative Physiology), who graduated in the summer of 2021, earned the “American Journal of Physiology-Heart and Circulatory Physiology 2023 Best Research Article Award” for his article titled “Acute Effects of Electronic Cigarettes on Arterial Pressure and Peripheral Sympathetic Activity in Young Nonsmokers.”

Dr. Joshua E. Gonzalez
Dr. William Cooke
Dr. Josh Gonzalez receiving his award at the American Physiology Summit. Also in the photo is AJP Editor-in-Chief Merry Lindsey and the winners of the best review article and best rapid report.

He wrote and published this article while still a PhD student at MTU along with his advisor and co-author Dr. William Cooke. 

The AJP-Heart and Circulatory 2023 Best Research Article Award is based on: 

  • The total number of citations the article has received since publication (11)
  • Total online article usage (4,100+)  
  • The Altmetric score of 17 (measure of social media/news media impact)

He will receive both an award and cash prize at the upcoming American Physiology Summit 2023  to be held April 20-23, 2023 in Long Beach, California.

American Journal of Physiology, Heart and Circulatory Physiology logo

“Engineering the Future of Human Health”: KIP featured at MSU-MTU Symposium

Dr. William Cooke (KIP), Dr. Carolyn Duncan (KIP), and Dr. Kevin Trewartha (CLS/KIP) were among 12 researchers from Michigan Tech who met with colleagues representing the College of Human Medicine at Michigan State University on March 13, 2023. Hosted by MSU in Grand Rapids, Michigan, this was the inaugural event of the collaborative research symposium between the universities.

Dr. Duncan and Dr. Trewartha presented during the “Neurological Disease and Aging Research” session, while Dr. Cooke presented at the “Cardiovascular Research” session.

In the fall, Michigan Tech will host the second symposium with Dr. Cooke as a co-sponsor. “This is an important collaborative opportunity, and I look forward to being among those who will be organizing the next collaborative meeting on October 27th–beautiful time to be in the UP,” he remarked when asked about the future event.

The full story and complete list of MTU and MSU researchers who gave presentations can be found in Tech Today.

Dr. Carolyn Duncan presented on “Balance and Functional Mobility” at the MSU-MTU symposium.
Dr. Kevin Trewartha’s presentation was titled “Aging and Cognition: Implications for Motor Learning and Sensorimotor Motor Control in Older Populations.”

KIP PhD Student Awarded Michigan Space Grant Consortium Fellowship

Kyle Wehmanen, PhD Student

Kyle Wehmanen, a PhD student and graduate teaching assistant, has been awarded a $5,000 graduate fellowship by the Michigan Space Grant Consortium, which is sponsored by NASA, for its 2023-2024 cycle. His project is entitled “Human Powered Locomotion on Variable Terrain: Implications for how to Move on Mars.”

More details about the MSGC and the complete list of undergraduate, graduate, and faculty recipients can be found in the Tech Today announcement from the Graduate School.