Category: Research

Call for Applications: 2023 Songer Research Award for Human Health

Undergraduate and graduate students in the Kinesiology and Integrative Physiology Department are encouraged to apply for the 2023 Songer Research Award for Human Health. Matthew Songer, (Biological Sciences ’79) and Laura Songer (Biological Sciences ’80) established these awards to stimulate and encourage opportunities for original research by current Michigan Tech students.

Students may propose an innovative medically-oriented research project in any area of human health. The best projects will demonstrate the potential to have a broad impact on improving human life. This research will be pursued in consultation with faculty members within the College of Sciences and Arts. The Songers’ gift and matching funds from the College will support two awards for undergraduate research ($4,000) and two for graduate research ($6,000), for research conducted over the Summer of 2023 and/or the following academic year.

Learn more about who is eligible to apply, how to apply, and how the funds may be used.

Submit applications as a single PDF file to the Office of the College of Sciences and Arts by 4:00 p.m. Monday, April 24, 2023. Applications may be emailed to djhemmer@mtu.edu. Any questions may be directed to David Hemmer (djhemmer@mtu.edu).

PhD Student Receives Award at the 2023 National Safe Patient Handling and Mobility Education Event

Ashley Hawke, PhD student

PhD student Ashley Hawke received the Gallagher Award at the 2023 National Safe Patient Handling and Mobility Education Event that took place in Glendale, AZ from March 20-23, 2023. This national event is hosted by the Association of Safe Patient Handling Professionals.

The award Ashley received is for her project proposal entitled “Effectiveness of Patient Handling Interventions on Reducing Musculoskeletal Disorder Risk in Healthcare Workers: A Study Proposal.” Below is her project’s abstract to learn more about Ashley’s work.

Background: Musculoskeletal disorders (MSDs) are extremely prevalent among healthcare workers, especially those who perform patient handling tasks. Previous research has found that sustained static and/or awkward working postures, frequent bending, repetitive and/or forceful work, and twisting were commonly associated with MSDs. The use of mechanical assistive devices reduces risks of MSDs during patient handling; however, availability and accessibility of equipment are common barriers to using these devices in clinical settings. Portable passive interventions, such as transfer slings, slider sheets, and exoskeletons have been proposed to assist with patient handling tasks as an alternative to mechanical assistive devices, but the effectiveness of these interventions in reducing MSD risk in healthcare workers is inconclusive. METHODS: In the proposed study, we will evaluate three passive patient handling interventions (transfer sling, slider sheet, and passive back-assist exoskeleton) in their ability to alter biomechanical and physiological responses associated with the development of MSDs when performing two standardized patient handling tasks: 1) turning a patient onto their side and 2) performing a sit to sit transfer. Twenty participants will be recruited to perform the tasks using an 80 kg mannequin in four different interventions: manual, using a transfer sling, using a slider sheet, and wearing a passive exoskeleton. Variables to be measured include muscle activity of the trunk, upper extremity, lower extremity muscles, shoulder/lumbar kinematics, kinetics, oxygen consumption, heart rate, energy expenditure, and rating of perceived exertion. FINDINGS: As this is a study proposal, no results are available at this time. CONCLUSIONS/IMPLICATIONS: Results from the proposed study will allow researchers to evaluate the biomechanical demands and physiological cost of each patient handling intervention and how together these may play a role in potentially reducing MSDs. Importantly, these findings may serve as a first step to developing more cost-effective and portable patient handling interventions.

KIP Alum Wins AJP 2023 Best Research Article Award

KIP alum Joshua Gonzalez (PhD, Integrative Physiology), who graduated in the summer of 2021, earned the “American Journal of Physiology-Heart and Circulatory Physiology 2023 Best Research Article Award” for his article titled “Acute Effects of Electronic Cigarettes on Arterial Pressure and Peripheral Sympathetic Activity in Young Nonsmokers.”

Dr. Joshua E. Gonzalez
Dr. William Cooke
Dr. Josh Gonzalez receiving his award at the American Physiology Summit. Also in the photo is AJP Editor-in-Chief Merry Lindsey and the winners of the best review article and best rapid report.

He wrote and published this article while still a PhD student at MTU along with his advisor and co-author Dr. William Cooke. 

The AJP-Heart and Circulatory 2023 Best Research Article Award is based on: 

  • The total number of citations the article has received since publication (11)
  • Total online article usage (4,100+)  
  • The Altmetric score of 17 (measure of social media/news media impact)

He will receive both an award and cash prize at the upcoming American Physiology Summit 2023  to be held April 20-23, 2023 in Long Beach, California.

American Journal of Physiology, Heart and Circulatory Physiology logo

“Engineering the Future of Human Health”: KIP featured at MSU-MTU Symposium

Dr. William Cooke (KIP), Dr. Carolyn Duncan (KIP), and Dr. Kevin Trewartha (CLS/KIP) were among 12 researchers from Michigan Tech who met with colleagues representing the College of Human Medicine at Michigan State University on March 13, 2023. Hosted by MSU in Grand Rapids, Michigan, this was the inaugural event of the collaborative research symposium between the universities.

Dr. Duncan and Dr. Trewartha presented during the “Neurological Disease and Aging Research” session, while Dr. Cooke presented at the “Cardiovascular Research” session.

In the fall, Michigan Tech will host the second symposium with Dr. Cooke as a co-sponsor. “This is an important collaborative opportunity, and I look forward to being among those who will be organizing the next collaborative meeting on October 27th–beautiful time to be in the UP,” he remarked when asked about the future event.

The full story and complete list of MTU and MSU researchers who gave presentations can be found in Tech Today.

Dr. Carolyn Duncan presented on “Balance and Functional Mobility” at the MSU-MTU symposium.
Dr. Kevin Trewartha’s presentation was titled “Aging and Cognition: Implications for Motor Learning and Sensorimotor Motor Control in Older Populations.”

KIP PhD Student Awarded Michigan Space Grant Consortium Fellowship

Kyle Wehmanen, PhD Student

Kyle Wehmanen, a PhD student and graduate teaching assistant, has been awarded a $5,000 graduate fellowship by the Michigan Space Grant Consortium, which is sponsored by NASA, for its 2023-2024 cycle. His project is entitled “Human Powered Locomotion on Variable Terrain: Implications for how to Move on Mars.”

More details about the MSGC and the complete list of undergraduate, graduate, and faculty recipients can be found in the Tech Today announcement from the Graduate School.

KIP Graduate Students Earn Top Honors at HRI Student Forum

PhD student Greg Miodonski was awarded First Place for the poster session at the Health Research Institute’s (HRI) Student Forum on February 24th. Greg, a student in Dr. Qinghui Chen’s (KIP) lab, presented his research project entitled “Exercise Training Upregulates SK Channel Function in the Hypothalamic Paraventricular Nucleus (PVN) of Sprague Dawley Rats.”

Greg Miodonski with his advisor Dr. Qinghui Chen.
Greg presenting his poster to judges at the HRI Student Forum.

PhD candidate Sherry Chen earned Third Place for her research project’s poster presentation entitled “The Role of Peripheral Orexin Systems and Brain-Derived Extracellular Vesicles in Salt Sensitive Hypertension.” Sherry’s advisor is Dr. Zhiying (Jenny) Shan.

“As a graduate student, it is a valuable experience to present my work in the HRI student forum as it facilitates networking with faculty and students outside of my department. During my poster presentation, I had the chance to meet with three judges, including Dr. Caryn Heldt, who is also working on extracellular vesicles. Dr. Heldt asked me questions about the characterizations of nanoparticles in hypertension and showed interest in collaborating in the future. Although our research interests differ – my project focuses on the biological function of the vesicles while Dr. Heldt’s team analyzes their features – we can still explore potential areas of overlap and collaborate based on what we study in common, the vesicles. Thanks for this great opportunity provided by HRI as it provides a platform for networking, exchanging ideas, and potentially new opportunities for research. I am happy to present my work and share new data in HRI next year.” —Sherry Chen on presenting at the HRI Student Forum.

Sherry’s Abstract:

Introduction- It has been reported that small extracellular vesicles (sEVs ≤ 200 nm) are implicated in the pathogenesis of multiple diseases including hypertension. However, the role of brain-derived sEVs in the development of salt sensitive hypertension (SSHTN) remains unclear.

Hypothesis- We hypothesized that brain-derived sEVs from high salt diet-treated rats can induce inflammation and oxidative stress in the central nervous system (CNS). To test this hypothesis, brain-derived sEVs of Dahl salt-sensitive rats with high salt (HS) diet (Dahl-HS-sEV) were used to treat primary brain neuronal cultures and microinjected into brain lateral ventricles, respectively, proinflammatory cytokines, chemokines, and oxidative stress markers were measured through real-time PCR or fluorescent probes. sEVs isolated from Sprague Dawley (SD) rats with normal salt (NS) diet (SD-NS-sEV) were used as a control.

Results– Data showed that Dahl-HS-sEV increased mRNA levels of inflammatory cytokines including TNFα (2.3-fold) and IL1β (3.7-fold), and chemokines including CCL2 (2.4-fold), CCL5 (2.1-fold), and CCL12 (4.2-fold), with significant difference (P<0.05). In addition, Dahl-HS-sEV treatment increased mRNA levels of transcription regulator, NF-κB (1.4-fold), and neuronal activation marker, c-FOS (1.3-fold), as well as CYBA (1.7-fold), in primary neurons, compared to SD-NS-sEV-treated cells (P<0.05). Confocal images showed that Dahl-HS-sEV significantly increased mitochondrial ROS levels, with total fluorescence intensity increased 1.6-fold relative to SD-NS-sEV treatment (P<0.01). SD-NS rats receiving intracerebroventricular injection of Dahl-HS-sEV had increased (P<0.05) PVN mRNA levels of IL1β (4.3-fold), CCL5 (2.6-fold), IL-6 (3.4-fold) and NOS2 (5.2-fold), compared to rats receiving SD-NS-sEV (5.5 μg/rat, n=4), 6h after injection.

Conclusion- These results suggested that in SSHTN, brain-derived sEVs may induce central inflammation and oxidative stress, which in turn results in an elevation of arterial blood pressure.

For the complete list of winners and departments that were represented, please read the Tech Today story that was published on March 7, 2023.

December KIP Seminar

Join us for the last seminar of the semester to close out the “Women in Health Science, Medicine, and Physiology” series.

Dr. Carrie Karvonen-Gutierrez and Dr. Erica Twardzik will be presenting their research and work. To learn more about the speakers, find their abstracts and biographies below.

Dr. Karvonen-Gutierrez’s Abstract: Among older adults (age 65+ years), declines in physical functioning, increases in disability and the relationship of falls with adverse outcomes including hospitalizations and death are well documented. However, evidence suggests that the mid-life period (40-64 years of age) is a critical window for the onset of poor physical functioning and falls, particularly in women. Women experience greater disability, more rapid declines in physical functioning, and more falls than do age-matched men. This presentation will overview the burden of physical functioning limitations, disability and falls among mid-life women and identify important correlates of these health outcomes. Key findings from the ongoing Study of Women’s Health Across the Nation, a prospective, multi-ethnic study of midlife women will be included to demonstrate important differences in the burden of physical functioning by key demographic measures.

Dr. Twardzik’s Abstract: Older adults with disabilities are a growing demographic group. People with disabilities represent 26.8% of the general population, and the prevalence of disability increases with age. People with disabilities, compared to non-disabled peers, are less likely to engage in physical activity and social participation, key components of healthy aging. Observed disparities are driven by a multifactorial set of environmental barriers and facilitators. This presentation will describe socio-environmental drivers of mobility among older adults and people with disabilities. Examples from recent work empirically testing relationships between built environment and mobility will be used to illustrate how environments shape mobility among people with disabilities. Environmental modification is needed to achieve societal inclusion and optimize individual participation among those aging with and into disability.

Free Falling: Dr. Carolyn Duncan to be featured on “Husky Bites”

Dr. Carolyn Duncan
Assistant Professor, KIP
Sarah Aslani
PhD Student, CLS

On Monday, November 14th, at 6:00 pm KIP’s Dr. Carolyn Duncan will be the latest guest on Husky Bites, a free and interactive Zoom webinar hosted by Dean Janet Callahan of the College of Engineering. Also joining in will be Cognitive and Learning Sciences PhD student Sarah Aslani, who is a member of Dr. Duncan’s Balance and Functional Mobility Lab.

During the 30-minute webinar, they will explore balance and fall prevention and discuss Dr. Duncan’s ongoing research on both topics. “We need greater understanding of exactly what affects our ability to regain our balance when we lose it. Not all risk factors affect balance in the same way. There are many unanswered questions, and that’s where our research comes in,” she explains in an interview she did for the College of Engineering Blog that highlights its Husky Bites guests.

To read the complete interview with Dr. Duncan and Sarah, go to the COE Blog. To tune in for their Husky Bites event, registration is required but free. All of the details can be found on the Husky Bites website.

Students conducting research in Dr. Duncan’s Balance and Functional Mobility Lab

From the Scientific Literature to the Field: KIP Graduate Students Present their Work at Two Recent Conferences

Graduate students in the Advanced Exercise Physiology Course (KIP 5000) recently attended several conferences and presented class projects collaboratively built through the first part of the semester. The course taught by Dr. Steven Elmer in the Department of Kinesiology and Integrative Physiology (KIP), tasked students with conducting a literature search to evaluate the direct and indirect effects of the COVID-19 pandemic on human health and society. In support of Exercise is Medicine on Campus Month, the student projects emphasized the important role that physical activity has in combating both chronic and infectious disease.

Midwest ACSM Conference

Master’s student Felix Cottet-Puinel and doctoral student Kyle Wehmanen attended the annual meeting for the Midwest Chapter of the American College of Sports Medicine held in Indianapolis, Indiana on October 20-22, 2022. The mission and purpose of the conference was to promote scientific advancement, disseminate information regarding sports, physical activity, and medicine, and foster collaborative relationships between students, educators, scientists, and physicians across the region. Felix and Kyle presented their class work during the first poster session of the event with great success. Visitors were highly engaged with the poster’s topic spotlighting the problematic synergy between multiple long-standing health pandemics (non-communicable diseases) and the crisis of the emergent COVID-19 pandemic. Their work also laid out evidence based on the HL-PIVOT Model (Healthy Living for Pandemic Protection) for leveraging healthy living behaviors including physical activity to combat these multiple pandemics. They shared ways the KIP students and faculty are working to increase activity and health in our community. Our Michigan Tech attendees also enjoyed learning outside their direct areas of study. Dr. Andrew Jagim from the Mayo Clinic delivered a fantastic keynote on nutrition in athletes and how they are often not meeting their basic needs. Also during the trip, Felix, Kyle, and several other KIP graduate students visited Dr. John Durocher at Purdue University Northwest to foster collaborative relationships across institutions. At the end of the day, it was a fantastic experience. Felix said, “I learned a great deal, and had a ton of fun presenting. The only thing I would change is making the poster session twice as long!”

Felix Cottet-Puinel presenting at Midwest ASM
Felix Cottet-Puinel
master’s student
Kyle Wehmanen
PhD student

Global and Community Engagement Conference

Master’s students Tyler Hampton and Gwyn Hamlin presented at the D80 Conference here at Michigan Tech University on October 29, 2022. The theme of the interdisciplinary conference was “Re-energizing Our Communities Through Service.” These students expanded upon the work described above to deliver an oral presentation to a broad audience consisting of students, staff, faculty, and community members. A key component of the presentation was highlighting the community service that the KIP Department provides delivering live and recorded physical activity workouts through a free program called UP & Moving. Attendees were very interested in how the general public views “physical activity” as a means to go to the gym, while Tyler and Gwyn pointed out that this could be something as simple as walking the dog or shoveling snow during our long winters here in the Upper Peninsula. These students also had the opportunity to listen to the keynote speaker Dr. Kurt Paterson, who presented “Global Engagement, Problem-Solving, or Impact.” Dr. Paterson’s return to Michigan Tech was very welcomed as he participated in the first D80 Conference held here. This is especially true since he really got the audience thinking at the end of his presentation. After the conference Gwyn said, “I enjoyed the setting of the conference and I think it went well. We were able to answer questions at the end and provide additional information on the importance of being physically active during the pandemic and beyond.”

Gwyn Hamlin
master’s student
Tyler Hampton master’s student

Attending these conferences helped KIP graduate students gain valuable experience bridging the gap from classroom learning to a professional setting while sharing their ideas in a supportive environment. Moving forward, we plan to capture this momentum and include more graduate and undergraduate students in similar work. Finally, the graduate students would like to thank the KIP Department for their support, and specifically, Dr. Elmer for his guidance throughout the process.

KIP Students and Faculty Participate in UP Medical Conference

Sherry Chen, PhD student, Poster Session Winner (tied 3rd place)
Isaac Lennox, MS student, Poster Session Winner (1st place)

Students and faculty from the Department of Kinesiology and Integrative Physiology and recently participated in the first annual Upper Peninsula Medial Conference, hosted by the Michigan Tech Health Research Institute, on August 26-28, 2022.

The focus of the conference was on rural health and health topics impacting rural communities (e.g., mental health, lifestyle medicine, diabetes, public health, orthopedics and sports medicine). Conference attendees included students, faculty, and clinicians from across the Upper Peninsula. The conference also provided continuing medical education credits for clinicians.

Graduate students Xingqian (Sherry) Chen, Isaac Lennox, Greg Miodonski, Isaac Wedig, and Kyle Wehmnanen presented their research and outreach-related projects. For the research category, Isaac Lennox and Sherry Chen earned awards for their poster presentations. For the physician’s choice category, Isaac Wedig and Kyle Wehmanen earned awards for their poster presentations. Isaac Lennox, Isaac Wedig, and Kyle Wehmanen, along with Dr. Elmer, delivered an interactive activity as part of the featured lecture on lifestyle medicine.

Isaac Wedig, PhD candidate, Physician’s Choice Winner (tied)
Greg Miodonski, MS student

Conference attendees also had the opportunity to tour the Exercise Physiology Laboratory and visit the Central Michigan University Physical Therapy Program – Satellite Campus. Dr. Chen and Dr. Elmer, served on the conference organizing committee. Dr. Elmer indicated that, based on feedback from attendees, the organizing committee is already discussing plans for improving the conference for next year.

Overall, the first annual Upper Peninsula Medial Conference was an excellent opportunity for students and faculty to showcase their work, learn more about rural health challenges, and network with clinicians. Thank you to the Department of Kinesiology and Integrative Physiology Faculty for supporting costs for our students to attend this conference.