Graduate School Newsblog

Author: Lois Hwang

Doctoral Finishing Fellowship – Fall 2023 Recipient – Adelina Oronova

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From the very beginning of my academic journey, the intersection of chemistry and biology has thrilled me, as it embodies the essence of interdisciplinary challenges that encourage innovative thinking. Having BS and MS in biochemistry, I joined the Chemistry Department at Michigan Technological University in August 2018 as a Fulbright Graduate Student from Ukraine. Under the mentorship of Dr. Marina Tanasova, I pursued chemical biology research to utilize small molecules produced through synthetic chemistry for the study of complex biological systems.
My Ph.D. research focuses on the development of tools for the targeted detection of disease-relevant sugar transporters (GLUTs) to advance diagnostic and imaging capabilities. Working in Dr. Tanasova’s lab has been an incredibly rich research experience, allowing me to master a diverse set of skills and carry out the whole research project from the beginning to the end. I truly enjoy the process of designing molecules, synthesizing them, and validating their properties through a range of analytical techniques. Witnessing the colorful array of fluorescent probes we have developed and applying them for cancer research has evoked excitement in me. I am genuinely excited about the potential outcomes of my research, as they contribute to the advancement of novel strategies for targeting cancers in both diagnostic and therapeutic applications. Collaborating with other researchers and students, sharing my research, and promoting a safety culture within my department and on the national level have been rewarding and enriching experiences for me during my Ph.D. I am grateful for the opportunities I have had during my graduate program. I am confident that the training I received at MTU has provided me with a solid foundation to realize my research aspirations.
I am honored to be selected as one of the recipients of the Doctoral Finishing Fellowship. I would like to thank the Graduate Dean Awards Advisory Panel and Dean for granting the fellowship to me during this crucial phase of my Ph.D. journey. It is indeed an invaluable opportunity to dedicate my time and efforts to writing my dissertation, preparing for the defense, and embarking on the next chapter of my scientific career. I would like to thank my research advisor Dr. Marina Tanasova for the support and guidance she provided over the last 5 years. Her belief in my potential paved the way for me to transition from a Master’s student to a doctoral candidate, and I am truly grateful for the mentorship and encouragement she has provided. Moreover, I wish to express my gratitude to the Chemistry Department, Dr. Sarah Green, my committee members, and all the individuals who have played a role in shaping me into an independent research scientist.

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Doctoral Finishing Fellowship – Fall 2023 Recipient – Ann Varghese

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I began my Ph.D. journey in Chemistry in the Fall 2019 under the guidance of Dr. Tatyana G. Karabencheva-Christova. Prior to joining MTU, I earned a master’s degree in Applied Chemistry from Mahatma Gandhi University and a bachelor’s degree in Chemistry from Calicut University, India. It was during my master’s program that I developed a profound interest in computational chemistry, which ultimately led me to pursue advanced studies in this fascinating field.

My research primarily focuses on exploring enzyme characteristics and mechanisms through the application of multilevel computational methods, including Molecular Dynamics (MD), Quantum Mechanics (QM), and combined Quantum mechanics/Molecular mechanics (QM/MM). During my Ph.D., I had the opportunity to contribute to NIH-funded projects on the non-heme Fe(II) and 2-oxoglutarate dependent oxygenase, Fat mass and Obesity Associated Protein (FTO), and the Zn(II) dependent metalloprotease, Matrix metalloproteinase-1 (MMP-1), both of which have crucial implications in various types of cancers. In the former project, I investigated the enzymatic mechanism of FTO with its major substrate, N6-methyladenine in single-stranded RNA, and explored the influence of clinically relevant mutations Arg316Gln and Ser319Phe on different stages of the catalytic cycle. In the latter, I unraveled the water-mediated catalytic mechanism of MMP-1, conformational dynamics and long-range correlated motions assisting in catalysis and the role of the catalytic and structural Zn(II) ions in the overall stability of enzyme.

I am immensely grateful to the Graduate Dean Awards Advisory Panel and the Dean for recognizing my efforts and awarding me the Doctoral Finishing Fellowship. I extend my heartfelt gratitude to my advisor, Dr. Tatyana G. Karabencheva-Christova, whose guidance and support have been invaluable throughout my Ph.D. journey. I also extend my thanks to all the faculty and staff in the Chemistry department for their encouragement and assistance.

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Doctoral Finishing Fellowship – Fall 2023 Recipient – Benjamin Barrios Cerda

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First, I would like to extend my gratitude to the Graduate Dean Awards Advisory Panel for recommending me for this prestigious award. I also want to acknowledge the department of Civil, Environmental, and Geospatial Engineering for its support during my PhD studies. Most importantly, I thank my advisor Dr. Daisuke Minakata, who has guided me throughout my journey and equipped me with critical thinking skills. Without his unwavering commitment, understanding, and guidance, I would not have achieved the level of proficiency as a PhD student that I possess today.

I have been passionate about chemistry ever since I was in high school. Chemistry teaches you how matter transforms, and because matter is everything we are surrounded by, chemistry essentially helps you to understand the world. Many of the big problems our world faces can be tackled in some way from a chemical perspective. Energy, pollution, water scarcity, health, are some of the global issues that are actively being addressed with chemistry.

During my PhD, I have translated my chemistry background to the environmental engineering field by understanding how pollutants are transformed in natural and engineered water systems, such as lakes, rivers, or water treatment plants. My philosophy is that the molecular details of those chemical reactions have a profound influence on the rate of degradation and products distribution. This led me to publish papers where I show that we can use results from molecular simulations to explain phenomena at the bulk scale such as how fast reactions take place. Understanding these details will enable engineers to optimize operational parameters on the removal of contaminants, and will inform environmental policy makers about the fate of toxic compounds once released to bodies of water.

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Doctoral Finishing Fellowship – Fall 2023 Recipient – Susan Mathai

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I started as a PhD student in Atmospheric Sciences at Michigan Tech in August 2018. My interest in Atmospheric Sciences began during an elective course I took while pursuing my master’s degree in physics at the National Institute of Technology (NIT Calicut). Since then, my interest in Atmospheric Sciences has grown, and I have been eager to learn more about it.
My doctoral research focuses on investigating the physical, chemical, and optical properties of aerosols, which are particles suspended in the atmosphere, specifically those emitted from biomass burning. Over the course of five years, with the support of my advisor and colleagues at Michigan Tech, I have gained valuable knowledge and experience that will undoubtedly benefit me in my future endeavors. Additionally, I had the opportunity to expand my exposure and understanding of the subject through an internship at Pacific Northwest National Laboratory (PNNL), where I worked with Dr. Swarup China. During my internship, I estimated the optical properties of tar ball particles that are formed during biomass combustion. I also studied the physical and chemical properties of aerosols from an Urban polluted region that is highly influenced by biomass burning.
I am grateful to the Graduate Dean Awards Advisory panel for granting me the finishing fellowship award and to my advisor, Prof. Claudio Mazzoleni, for his unwavering support and guidance throughout my PhD journey. I also thank my mentor at PNNL, Dr. Swarup China for his hard work and dedication in helping me complete my PhD. Additionally, I express my thanks to both my current and former research group members for engaging in excellent discussions and fostering a spirit of teamwork. I eagerly anticipate defending my thesis and advancing along my chosen career path.

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Doctoral Finishing Fellowship – Fall 2023 Recipient – Hrishikesh Gosavi

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Since I began learning the basics of science, the effects of vibrations on environments has always fascinated me. As Nikola Tesla said, “If you want to find the secrets of the universe, think in terms of energy, frequency and vibration.” It was with this aim that I started my Ph.D journey in Fall 2020.

My research has been in regards with “Metastructures”. These are unique structures which absorb vibrations in a system in particular frequency range, often called as ”bandgap”. It is because of this bandgap phenomenon that metastructures are widely used to mitigate vibration effects. Owing to large number of applications, it becomes important to estimate bandgaps in a metastructure to predict the frequency range in which the vibrations will be absorbed so that metastructures can be designed for various applications.

Through my research, I have aimed to developed new methods to estimate these bandgaps. The current methods available in the literature require a physics-based model of the metastructure (analytical model, finite/spectral element model) in order to estimate bandgaps. However, for various anisotropic materials, the material properties are difficult to quantify accurately which makes the physics-based model inaccurate. My research aims to overcome these limitations by developing methods which estimate bandgaps using purely experimental data. We have used the experimental data to study how a vibration wave is propagating through the metastructure (dispersion curve) and estimated bandgaps. Various other techniques such as substructuring, data-driven modeling algorithms were utilized. The developed techniques considerably reduced the design efforts required and made the entire design process much easier.

The funding provided by this fellowship will truly be helpful for me in putting all my energies in finishing my thesis in time and complete my Ph.D.!
I am grateful to the Graduate School for granting me this fellowship.
My advisor, Dr. Sriram Malladi has been more than helpful in guiding me through various ups and downs throughout my Ph.D journey. I am truly thankful for the relentless support he and his family has given me. Last but certainly not the least, I am thankful to my family i.e. my wife and my parents for their support in every aspect of my journey!

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Doctoral Finishing Fellowship – Fall 2023 Recipient – Komal Chillar

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I joined the Ph.D.in Chemistry program at Michigan Tech in Fall 2018. Prior to this, I obtained a Bachelor’s degree in Chemistry from Miranda House, University of Delhi, New Delhi, India in 2016 and Master’s in Organic Chemistry from Maharshi Dayanand University, Rohtak, India in 2018. During the course of my Ph.D., I honed multiple skills needed for the organic laboratory work, and developed various interpersonal skills including communication, presentation, critical thinking, problem-solving, collaboration, leadership qualities and many more. These skills have not only contributed to my research success but have also shaped me into a confident and capable professional.

As an organic chemist, to accomplish the research objectives, I successfully synthesized various small and macromolecules that served as a monomer for oligodeoxynucleotides. This process involved the utilization of various instrumental analysis techniques. During my research, I focused on the synthesis of sensitive oligodeoxynucleotides under mild deprotection and cleavage conditions. Sensitive oligodeoxynucleotides are the DNA nucleosides that are unstable to harsh deprotection and cleavage conditions. The results of my work have been published in the New Journal of Chemistry in 2023. Furthermore, I developed a method for the direct quantification of the oligodeoxynucleotides using the HPLC peak area. This method not only eliminated the need for additional steps in quantification and purification but also saved valuable time for the researchers. The details of this method were published in PeerJ Analytical Chemistry in 2022. Additionally, I was able to achieve the 49 bases long oligodeoxynucleotides which could retain the sensitive groups under mild deprotection and cleavage conditions. These sensitive groups are believed to be the modifications present in the human genome resulting in disease-cause. The manuscript on this accomplishment is under review in a prestigious Peer-Reviewed Journal.

I would also like to express my sincere gratitude towards the Graduate Dean Awards Advisory Panel and the Dean for providing me the Doctoral Finishing Fellowship for Fall 2023. This fellowship will help me to focus on my research goals while accomplishing all the degree completion timelines, including writing and defending my dissertation to graduate timely. Finally, I would like to sincerely thank my advisor Dr. Shiyue Fang whose unwavering support, guidance, and mentorship have been invaluable throughout my Ph.D. journey to help me to expand my knowledge and professional growth in the field.

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Doctoral Finishing Fellowship – Fall 2023 Recipient – Mehnaz Tabassum

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Ever since my early days as an undergraduate student, I have been captivated by the potential of technology to revolutionize our daily lives. Michigan Technological University has provided an enriching environment for my research endeavors. The collaborative spirit among faculty members and the vibrant research community have fostered an environment for innovative ideas and cross-disciplinary collaborations. Engaging in stimulating discussions with brilliant minds and participating in cutting-edge projects have amplified my intellectual growth and fortified my passion for pushing the boundaries of knowledge in vehicular networking.

I am thrilled to share my remarkable journey as a doctoral candidate at Michigan Technological University. I started my PhD in Fall 2018 in the Electrical and Computer Engineering department. Throughout my doctoral journey, I have dedicated myself to unraveling the complexities of vehicular networking, exploring its intricacies one discovery at a time. By delving into areas such as intelligent transportation systems, vehicle-to-vehicle (V2V) communication, and infrastructure-to-vehicle (I2V) interactions, I aim to contribute to the seamless integration of vehicles into our evolving smart cities.

I am immensely grateful for the support of my advisor, Dr. Aurenice Oliveira, whose guidance, expertise, and unwavering encouragement have been instrumental in shaping my research trajectory.

To all aspiring researchers and technologists, I urge you to embrace your passions and fearlessly pursue your dreams.

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Doctoral Finishing Fellowship – Fall 2023 Recipient – Ponkrshnan Thiagarajan

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Growing up in a township full of scientists and engineers, I have always been curious about how things work. This led me to pursue a bachelor’s in engineering from Nehru Institute of Engineering and Technology affiliated with Anna University, Chennai. I then pursued a master’s from the esteemed Indian Institute of Technology, Madras where I delved into diverse research projects that captivated my interest. Fueled by this newfound interest, I started my journey as a Ph.D. student eager to tackle intriguing and fundamental challenges within the field of engineering.

I started working on my Ph.D. in the Fall of 2019 at the Computational Mechanics and Machine Learning Lab led by Dr. Susanta Ghosh at Michigan Tech. The focus of my research is on understanding the uncertainties associated with the predictions of computational and machine-learning models. Any model, computational or data-driven, is a representation of a physical phenomenon. We develop such models to understand the world around us better. However, predictions of such models are not always reliable due to the uncertainties associated with them. These uncertainties could arise for various reasons such as natural variability in the systems we study, assumptions in developing these models, numerical approximations, lack of data, etc. In order to use these models in real-life scenarios, quantifying these uncertainties is crucial. My research involves developing novel techniques to quantify the uncertainties, use these uncertainties to improve the model’s performance, and explain the reasoning behind the uncertainties. In my first project, we developed a Bayesian neural network-based machine-learning model that can reliably classify breast histopathology images into benign and malignant images. In addition, the model can quantify uncertainties associated with the predictions. We further developed techniques to explain the uncertainties and use them to further improve the model’s performance. In my second project, we developed novel loss functions for Bayesian neural networks and showed their advantages over the state-of-the-art in image classification problems. I am currently working on quantifying uncertainties in computational models that are used to characterize material behavior and extending the first two projects for several other applications.

I would like to thank my advisor Dr. Susanta Ghosh for giving me the opportunity to carry out this exciting research as well as for his immense help and guidance throughout the process. I thank the Graduate Dean Awards Advisory Panel and the dean for recommending me for this award. It is an honor. I thank the graduate school and the Department of Mechanical Engineering-Engineering Mechanics for their constant support.

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Doctoral Finishing Fellowship – Fall 2023 Recipient – Chen Zhao

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I started my Ph.D. journey at Michigan Tech in the fall of 2019 by joining the CS&E Ph.D. program at the Department of Applied Computing. Throughout my time at Michigan Tech, I have had the privilege of working at the Laboratory of Medical Imaging and Informatics under the guidance and supervision of Dr. Weihua Zhou. My Ph.D. research has been dedicated to the development of medical imaging analysis algorithms using deep learning techniques. Specifically, my research has focused on areas such as medical image segmentation utilizing prior knowledge, multiscale information fusion, and topology-based image semantic segmentation through graph neural networks. These algorithms and models that I have developed have been successfully applied to the analysis of coronary artery angiograms, contributing to computer-aided diagnosis and treatment of coronary artery disease.

I would like to express my sincere gratitude to the Department of Applied Computing for providing me with an exceptional research environment and the resources necessary for my research. I am especially grateful to the Graduate School and the Graduate Dean Awards Advisory Panel for recognizing my research efforts and granting me the Finishing Fellowship award. This award allows me to dedicate my time and efforts to the completion of my final research projects and the writing of my dissertation.

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Doctoral Finishing Fellowship – Fall 2023 Recipient – Hanrui Su

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In the fall of 2019, I embarked on my Ph.D. program in Environmental Engineering at MTU, working under the guidance of Dr. Yun Hang Hu. My research focus revolves around environmental pollution control technology, functional materials, and energy conversion systems. Throughout my doctoral journey, I have dedicated my efforts to developing an ultrafast alternative to the sluggish oxide ion transfers observed in conventional solid oxide fuel cells.
Our research endeavors led us to the discovery of a new type of fuel cell, known as a carbonate-superstructured solid fuel cell, which exhibits enhanced efficiency and performance by utilizing hydrocarbon fuel directly. This technology offers numerous advantages, including fuel flexibility, improved durability, and increased energy conversion efficiency at relatively lower operating temperatures. Presently, I am actively engaged in improving the fuel cell performance and exploring the underlying mechanisms. My goal is to contribute to the advancement of sustainable technologies that can shape a greener future and generate a positive impact on society.
I would like to express my sincere gratitude to the Graduate Dean Awards Advisory Panel for awarding me the finishing fellowship. This award will afford me the invaluable opportunity to dedicate my full attention to completing my dissertation and preparing for my defense. I am sincerely appreciating my advisor, Dr. Yun Hang Hu, whose invaluable guidance, conceptual insights, and technical expertise have been instrumental in shaping me into an independent researcher. I also extend my gratitude to my committee members, Dr. Miguel Levy, Dr. John Jaszczak, and Dr. Kazuya Tajiri, as well as my lab members, family, and friends, whose unwavering assistance and support have been integral to my success throughout my doctoral journey.

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