Tag: Biomedical Engineering

Doctoral Finishing Fellowship – Summer 2024 Recipient – Seyedmostafa Rezaeitaleshmahalleh

Mostafa Rezaeitaleshmahalleh standing outdoors under a tree
Mostafa Rezaeitaleshmahalleh – Biomedical Engineering

As a final-year PhD candidate in Biomedical Engineering at Michigan Tech, my research revolves around understanding complex blood flow patterns and their implications for aneurysm development and rupture. Specifically, I focus on two types: intracranial aneurysms and abdominal aortic aneurysms.

In my dissertation, I utilize computational fluid dynamics to simulate blood flow within 3D vascular models extracted from medical imaging data of patients with aneurysms. By applying innovative computational methods, I analyze velocity and wall shear stress characteristics within the aneurysm. This approach has led to the development of new metrics that enhance our ability to distinguish between ruptured and unruptured aneurysms, shedding light on flow conditions indicative of potential rupture. Moreover, I’ve devised a systematic method for assessing the composition of intraluminal thrombosis (ILT). Using deep learning algorithms, I identify the ILT region within the vascular model and employ radiomics to analyze its structural properties. This analytical framework provides novel insights into the ILT region, thereby enhancing our ability to identify abdominal aortic aneurysms at heightened risk of rupture. The final aspect of my doctoral research is to develop a nearly automated pipeline to run CFD simulations with minimal user interaction. This automated workflow aims to eliminate time-consuming and labor-intensive steps, making the process more efficient and user-friendly.

My hope is that this work will one day eliminate the current barrier to integrating CFD simulation into clinicians’ workflow and help doctors leverage CFD simulation in their decision-making process. The quantified measures of flow characteristics and ILT composition may be utilized in the clinical setting to better identify which aneurysms are at high risk of rupture. This could guide clinical decision-making to determine if aneurysm surgery prior to rupture is worth the risk, or if an aneurysm is likely to remain stable, posing minimal risk to the patient’s health.

I want to express my sincere gratitude to the Graduate Dean Award Advisory Panel for granting me this award. I also want to thank my advisors, Dr. Jingfeng Jiang, and my committee members, Dr. Sean Kirkpatrick, Dr. Hoda Hatoum, and Dr. Weihua Zhou, for their invaluable guidance and expertise throughout my time at Michigan Tech. Their mentorship has been crucial in shaping my research and academic journey.

DeVlieg Graduate Research Recipient – Summer 2024 – Fatemeh Razaviamri

Fatemeh Razaviamri standing outside with body of water, trees, and cityscape behind
Fatemeh Razaviamri – Biomedical Engineering

I am a third-year PhD student in the Biomedical Engineering department. My research focuses on designing polymeric biomaterials for antimicrobial, hemostatic, and wound healing applications under the supervision of Dr. Bruce Lee. Currently, I am working on a project aimed at developing a novel, antimicrobial hemostatic agent inspired by the strong adhesive properties of mussel adhesive proteins.

Hemorrhage is one of the leading preventable causes of death associated with trauma. Additionally, trauma patients are at a higher risk for developing infection, leading to substantial morbidity and mortality. I aim to develop a novel and portable hemostatic agent that could achieve hemorrhage control in a prehospital setting and prevent infection. This powder-form hemostatic agent can be activated by hydration through the patient’s bodily fluid or blood, which greatly simplifies the criteria for packaging and storage. The proposed hemostatic agent provides multiple mechanisms to prevent infection, including the ability to kill drug-resistant bacteria. The ability to disinfect the wound site in a prehospital setting will limit complications associated with infection and will greatly improve the rate of recovery.

I am immensely grateful for the support provided by the DeVlieg Foundation and the Graduate Dean Awards Advisory Panel. With their support, I will spend the summer conducting in vivo hemostatic and infected wound healing tests using a mouse model to evaluate the rapid and effective hemostatic properties of the designed hemostatic agent, as well as its ability to promote the infected-wound healing.

Doctoral Finishing Fellowship – Summer 2024 Recipient – Mohanish Kishor Chandurkar

Mohanish Chandurkar standing outdoors with wooded mountain view behind
Mohanish Kishor Chandurkar – Biomedical Engineering

As I approach the culmination of my graduate studies, I am profoundly grateful for the opportunity to express my deepest gratitude for being selected as a recipient of the Graduate Finishing Fellowship. This award not only signifies a recognition of my academic achievements but also serves as a testament to the invaluable support and encouragement I have received throughout my journey.

Being inspired by the healthcare researchers and professionals and my background in engineering motivated me to pursue my career in Biomedical engineering to contribute to healthcare innovation. My PhD work focuses on the fundamentals of mechanobiology to understand cardiovascular health and disease conditions. Specifically, it focuses on the role of blood flow profiles in tuning the vascular function on cell level to better understand cardiovascular diseases.

Throughout my time in graduate school, I have been fortunate to work alongside my mentor Dr. Sangyoon Han, my committee and colleagues who played an important role in shaping my academic and professional development. The continued support from Biomedical engineering department, graduate school and HRI played a significant role in pursuit of my educational experience.

I extend my heartfelt appreciation to the selection committee for their confidence in my ability and for their investment in my future. Thank you for believing in me and for empowering me to pursue my dreams.

Doctoral Finishing Fellowship – Spring 2023 Recipient – Nikhil Mittal

My passion for research developed early on in my life as I saw my father going to the laboratory, doing research using cool equipment. He inspired me to ask intriguing questions in life and find answers to them. My journey in biomedical research began during my undergraduate in biotechnology where I was introduced to the concepts of cell and molecular biology research and its application. In my undergrad, I got firsthand experience of working in a research lab where I learned to independently run PCR (polymerase chain reaction) and electrophoresis gels. This sparked my curiosity to further develop my career in research. That’s when I joined Michigan Tech as a master’s student in the biomedical engineering department. At Michigan Tech, I learned about the development of biomaterials and their physiological applications. During this time, I also got the opportunity to do an internship at a Biotech company.

My research experience during my master’s and internship motivated me in advancing my professional career and join PhD. In 2018, I got the opportunity to join Dr. Sangyoon Han’s Mechanobiology laboratory. My research focus is to understand the mechanism of how cells sense the stiffness of their surrounding environment. Specifically, I am investigating how and when exactly the mechanical link between a cell and its extracellular matrix (ECM), known as focal adhesions, sense different stiffness and molecules involved in the process. For this purpose, I use soft elastic gels (biomaterials), live-cell imaging microscopy, and machine learning-based image analysis to study how different ECM stiffness can affect the force transfer through these connections. Mechanical stiffness of the matrix has been known to dictate cell behavior such as their survival, proliferation, migration, altered drug response and even tumor progression. With my research, I aim to provide new insights in physiology and pathophysiology for developmental disorders, cancer progression and metastasis and designs of tissue transplantation. This is critical in determining treatment strategies for these diseases. Along with research, I was fortunate to mentor and supervise many undergraduate and masters’ students for their respective projects. I also got the opportunity to present my work at different conferences and win grants for my research.

I am grateful to my advisor Dr. Sangyoon J. Han for his continued support and guidance over my PhD years at Michigan Tech. I am also grateful to my committee and biomedical engineering department for supporting me with my PhD journey. I am thankful to the Graduate school and Graduate Dean Awards Advisory Panel for granting me this fellowship. This fellowship will help me dedicate all of my time to complete my dissertation.

Dean’s Award for Outstanding Scholarship – Fall 2022 Recipients

Congratulations to the following students on receiving the Outstanding Scholarship Award!

Jesse Anderson- Atmospheric Sciences
Md. Saleh Akram Bhuiyan- Biomedical Engineering
Aynaz Biniyaz- Civil Engineering
Julian Blann- Accounting
Sarvada Hemant Chipkar- Chemical Engineering
Jay Czerniak- Business Administration
Joshua Golimbieski- Engineering Management
Ronald Kyllonen- Mechanical Engineering
Ikechukwu Emmanuel Okoh- Mechanical Eng-Eng Mechanics
Rohit Sunil Pandhare- Mechanical Eng-Eng Mechanics
Peng Quan- Forest Science
Sambhawana Sharma- Physics
Emily Shaw- Engineering – Environmental
Shardul Tiwari- Environmental & Energy Policy
Modupe Omolara Yusuf- Rhetoric, Theory and Culture

Dean’s Award for Outstanding Scholarship – Spring 2022 Recipients

Congratulations to the following students on receiving the Outstanding Scholarship Award!

Jiban Krishna Adhikary- Computer Science
Sarah Anderson- Accounting
Samantha Appleyard- Engineering Management
Chinmoyee Das- Forest Science
Talva Jacobson- Indust Heritage & Archaeology
Shabnam Konica- Mechanical Eng-Eng Mechanics
Akhil Manoshkumar Kurup- Computer Engineering
Yunxiang Ma- Civil Engineering
Andrew Puyleart- Applied Physics
Reihaneh Samsami- Civil Engineering
Ariana Smies- Biomedical Engineering
Mitchel Timm- Mechanical Eng-Eng Mechanics
Erin Vandenbusch- Business Administration
Emmeline Wolowiec- Geology
Upendra Yadav- Mechanical Eng-Eng Mechanics
Shijia Yan- Statistics

Dean’s Award for Outstanding Scholarship – Fall 2021 Recipients

Congratulations to the following students on receiving the Outstanding Scholarship Award!

Sandip Aryal- Physics
Tanner Barnes- Forest Ecology & Mgmt
Jennifer Butina- Business Administration
Jennifer Carolan- Accounting
Jessica Daignault- Civil Engineering
Domenicca Mileth Guillen Pachacama- Geology
Srinivas Kannan- Biomedical Engineering
Shreyas Sunil Kolapkar- Mechanical Eng-Eng Mechanics
Nurun Nahar Lata- Atmospheric Sciences
Emma Lozon- Rhetoric, Theory and Culture
Ninad Mohale- Materials Science and Engrg
Shane Oberloier- Electrical Engineering
Ahmed Umair Riyas- Engineering Management
Abu Sayeed Md Shawon- Applied Physics
Tessa Steenwinkel- Biological Sciences

DeVlieg Graduate Summer 2022 Research Recipient – Brennan Vogl

I am a second-year PhD student in the Biomedical Engineering department. I started my undergraduate degree at Michigan Tech in 2016, I enjoyed my time here so much I decided to come back to become a PhD student in the Biofluids lab in 2021. My field of research is cardiovascular hemodynamics, the study of how blood flows through the cardiovascular system. I work with physicians to investigate how cardiovascular diseases (aortic stenosis, hypertension, mitral regurgitation, etc.) can alter the blood flow of the heart.

I am immensely grateful for the support provided by the DeVlieg Foundation and the Graduate Dean Awards Advisory panel. With their help, I will be able to spend the summer investigating changes to left atrial flow dynamics in patients with atrial fibrillation (AF) and who have received treatment for AF. I am hopeful that this research will provide a basic engineering framework to conduct computational simulations of AF and improve the clinical knowledge to provide the best therapy possible for patients with AF.

Michigan Tech gratefully acknowledges support from The DeVlieg Foundation for the DeVlieg Summer Research Award.

Michigan Space Grant Consortium graduate fellowship application support

The Graduate School is offering support services to assist graduate students in applying for the Michigan Space Grant Consortium’s Graduate Fellowship, including a workshop and one-on-one writing support.

MSGC’s Graduate Fellowship opportunity supports graduate students from affiliate
institutions who are conducting research and public service projects relevant to NASA’s strategic interests as expressed in NASA’s 2014 & 2018 Strategic Plans, specifically, research focused on aerospace, space science, and earth system science. Graduate students working in other, related science, technology, engineering, and mathematics fields are also eligible to apply. Starting this year, MSGC is piloting an expanded definition of STEM to include support for interdisciplinary projects that include art, so graduate students conducting research and projects relevant to NASA’s strategic interests in disciplines not traditionally considered STEM, such as the humanities or social sciences, are likewise encouraged to apply.

Fellowship recipients are awarded $5,000. To be eligible, applicants must be U.S. nationals, have a good academic record, and be in good academic standing. Women, under-represented minorities, and persons with disabilities are strongly encouraged to apply. Students currently receiving MSGC Fellowships are eligible to reapply.

Workshop information: Overview and tips from an MSGC Fellowship reviewer
Date and Time: Friday, September 17th, from 11:00 AM – 11:50 AM
Location: Admin 404
Presenter: Will Cantrell, Associate Provost and Dean of the Graduate School
Host: Sarah Isaacson, GLAS Program Director, sisaacso@mtu.edu
Register here: https://forms.gle/RSPYtUHVD6Yjimou6
A recording of the workshop will be available beginning September 21st.

Wednesday, Nov. 3 at noon — Internal deadline for undergraduate and graduate fellowship proposals
Wednesday, Nov. 10 at 5 p.m. — Final materials, after review and approval by SPO, must be uploaded to MSGC by the applicant

For more information and specific application instructions, visit the MSGC website and the MTU Graduate School’s MSGC web page.