Tag: BME

Stories about Biomedical Engineering.

Moldable Nanocomposite Hydrogel System

Injectable One-Component Adhesive
Injectable One-Component Adhesive

A Moldable Nanocomposite Hydrogel Composed of a Mussel-Inspired Polymer and a Nanosilicate as a Fit-to-Shape Tissue Sealant” was published in Angewandte Chemie International Edition by Yuan Liu, Hao Meng, Zichen Qian, Ni Fan, Wonyoung Choi, Feng Zhao, and Bruce P. Lee.

DOI: 10.1002/anie.201700628

The paper concerns existing injectable sealants and tissues adhesives, which have difficulty adhering to surfaces with a complex and non-flat geometry (i.e., sealing the convex contour of a sutured anastomosis). They require a mixing tip for mixing liquid precursor solutions, and may use cytotoxic chemical activators to initiate the solidification of the adhesive.

The research team is designing a moldable hydrogel that can function as a fit-to-shape tissue sealant employing adhesive chemistry utilized by marine mussels. Initially, the adhesive is injectable as a gel, able to be remolded to different shapes. It can be applied around the contour of a tissue surface. Over time, the adhesive solidifies and adapts to the new shape, sealing defects on the tissue.

The exhibited burst pressure is suitable for sealing sutured intestinal anastomosis, renal vein, and other applications.

Video of Conventional Sealant
Video of Conventional Sealant

https://youtu.be/bTZZVColX50

Video of Hydrogel Sealant
Video of Hydrogel Sealant

https://youtu.be/qrWxEDLzHqc

Engineering Students Participate in URS 2017

URS

Winners Announced!

Brian Flanagan
Computer Engineering
The Effects of Uncertain Labels on Damage Assessment in Remotely Sensed Images
SECOND PLACE WINNER

Drew Hanover
Mechanical Engineering
Building-to-Grid Predictive Power Flow Control for Demand Response and Demand Flexibility Programs
THIRD PLACE WINNER

Trevyn Payne
Chemical Engineering
Separation of Individual Components from Lithium-Ion Batteries
HONORABLE MENTION

Hannah Marti
Biomedical Engineering
Psychophysiological Effects of Acute Mindfulness Meditation
HONORABLE MENTION

Several undergraduate students in engineering disciplines participated in Michigan Tech’s Undergraduate Research Symposium (URS) on March 17, 2017, in the Rozsa Lobby. Hosted by the Pavlis Honors College, the URS highlights the amazing cutting-edge research being conducted on Michigan Tech’s campus by some of our best and brightest undergraduate students.

READ THE ABSTRACTS

Participating engineering students included:

Dakota Anderson
Biomedical Engineering, Electrical Engineering
Improving Upper-Body Muscle Conditioning While Training at Low Intensities

Alicia Ball
Chemical Engineering
Effect of pH & Mineral Chemistry on Settling of Mineral Particles

Erica Coscarelli
Environmental Engineering
Impact of Dissolved Organic Matter & Its Transformation to Ultraviolet Photolysis Process in Engineered Water & Wastewater Treatment Systems

Aaron Dean
Mechanical Engineering
Effectiveness of Using SHRP2 Naturalistic Driving Study Data to Analyze Driver Behavior at Highway-Rail Grade Crossings

Mary Elizabeth Galbraith
Chemical Engineering
Unconventional Rare Earth Element Resources

Rebekka Guyon
Geological Engineering
Production of Biocementation from the Stimulation of Iron-Oxidizing Bacteria to Mitigate Dust Susceptibility

William Hughes
Mechanical Engineering
Investigation of Fuel Injection Systems- Fundamental Nozzle Cavitation Studies

Emily Hunt
Materials Science and Engineering
3D Printed Super-Bainitic Steel

Michelle Kelly
Environmental Engineering
Within-Reach Variation in Nitrification and Denitrification Rates in Lake Superior Tributaries

Ami Kling
Biomedical Engineering
Determination of the Effects of Hyperthermic Ablation on the Microstructure of Type I Collagen

Allysa Meinburg
Biomedical Engineering
Sensorized Suture Anchor for Real Time Monitoring of Tensile Loads

Alex Miltenberger
Applied Geophysics
Multiple-Point Geostatistical Simulation of Fracture Networks Using Secondary Ground Penetrating Radar Information

Zachary Oldenburg
Chemical Engineering
A Preliminary Economic Feasibility Study for the Recycling of Lithium-Ion Batteries

Emily Petersen
Materials Science and Engineering
Emergence of Home Manufacturing in the Developed World: Return on Investment for Open-Source 3-D Printers

Denada Planaj
Geological Engineering
Modeling Shallow and Deep Seated Landslides in Wayanad District, Kerala, India

Violet Thole
Materials Science and Engineering
Structure Property Relationships in Next Generation Ballistic Fibers

Ben Updike
Chemical Engineering
Preliminary Quantum Chemical Investigations on the Designing of Effective Catalysts for the Haber Process

Travis Wigstrom
Chemical Engineering
A Better Approach to Tritylation of Alcohols

Erica Anderson
Geological Engineering
Modeling the Potential Travel Paths of Post-Wildfire Debris Flows

Yani Beeker
Materials Science and Engineering
Open-Source Parametric 3-D Printed Slot Die System for Thin Film Semiconductor Processing

Katie Bristol
Applied Geophysics
Rock Magnetic Investigation of Carbonaceous Chondrules from the Allende Meteorite

Jeffrey Brookins
Materials Science and Engineering
Prototyping & Characterization of Zinc-Based Bioabsorbable Vascular Ligating Clips

Andrew Bruning
Mechanical Engineering
Generating Monodisperse Oxidized Methacrylated Alginate Microbeads with Specific Encapsulation Factors

Derek Burrell
Electrical Engineering
Performance Analysis of Stationary Hadamard Matrix Diffusers in Free-Space Optical Communication Links

Elisha Earley
Biomedical Engineering
Evaluating Novel Biodegradable Stent Materials

Simon Eddy
Materials Science and Engineering
Tungsten Disulfide as a Counter Electrode in Dye-Sensitized Solar Cells

Meghan Friske
Biomedical and Electrical Engineering
Characterization of Electrospun Nanofiber Scaffold for Wound Healing Applications

Samuel Gaines
Civil Engineering
Structural Health Monitoring Using UAV’s & Kinect Sensors

Jackie Harris
Chemical Engineering
Investigation into the Free Radical Scavenging Activity of Novel Nitroxide Derivatives

Carly Joseph
Biomedical Engineering
Development of a Novel Injectable Nitric Oxide Releasing Fibrin Microgel Composite Hydrogel for Tendon Repair

Ryan Kibler
Environmental Engineering
Understanding Lake Superior Warming Through Observational Data & Model Results

Jeremy Luebke
Environmental Engineering
Changes in Tropospheric Ozone Formation With a Reduction in PM Over China

Mary Kate Mitchell
Chemical Engineering
Predicting the Rejection Efficiencies of Toxicologically Relevant Organics in Reverse Osmosis of Wastewater Reclamation Processes

Charles Newlin
Materials Science and Engineering
The Effects of Nano-Sized Particles in Ultrahigh Carbon Steels

Thomas Page
Mechanical Engineering
Linear Traverse Design Project for Research Applications in the Cloud Chamber

Emily Praznik
Environmental Engineering
Macroinvertebrates in Hammel Creek

Hao Qin
Materials Science and Engineering
Synergistic Effect of Graphene-Oxide-Doping and Microwave-Curing on Mechanical Strength of Cement

David Ross
Biomedical Engineering
Covalently Bonded Collagen Coating on PDMS Improved Human Mesenchymal Stem Cell Sheet

Philip Staublin
Materials Science and Engineering
Modeling Biocorrosion of Zinc Alloys in Endovascular Environment

Valeria Suarez
Geological Engineering
Risk Assessment and Slope Stability Modelling of a Transportation Corridor in Hindu Kush Range

Brendan Treanore
Materials Science and Engineering
Substrate Active Cooling for Weld Based 3D Printing

Aligned Nanofibrous Cell-Derived Extracellular Matrix for Anisotropic Vascular Graft Construction

Fibroblast Cell Sheet
Fibroblast Cell Sheet

Authors: Qi Xing (former postdoc researcher), Zichen Qian (PhD candidate), Mitchell Tahtinen (former undergraduate researcher), Ai Hui Yap (Houghton High School student), Keegan Yates (former undergraduate researcher), and Feng Zhao (associate professor, biomedical engineering).
Journal: Advanced Healthcare Materials

10.1002/adhm.201601333

This article describes vascular grafts, which are in great demand due to the high occurrence of cardiovascular diseases. A tissue engineered vascular graft was developed for the application of bypassing coronary arteries. It is a completely biological vascular graft, which can avoid immune rejection after transplantation. The graft is mechanically strong, which is fabricated by combining naturally derived nanofibrous biomaterials, stem cell engineering, and bioreactor technologies.

Vascular Graft Fabrication Process
Vascular Graft Fabrication Process

Engineering Students Perform Well at 2017 Graduate Research Colloquium

GRC 2017The 2017 Graduate Research Colloquium (GRC) was held on February 15-16 in the Memorial Union Ballroom. There were oral and poster presentation. The banquet was held on the evening of February 16.

VIEW THE PHOTO GALLERY

Following is a complete list of winners:

Oral Presentation Competition

  1. 1st Place: Kevin Sunderland, Department of Biomedical Engineering
  2. 2nd Place: Teresa Wilson, Department of Physics
  3. 3rd Place: Andrew Chapp, Department of Kinesiology and Integrative Physiology
  4. Most Attended: Muraleekrishnan Menon, Department of Mechanical Engineering – Engineering Mechanics
  5. Most Attended: Niranjan Miganakallu, Department of Mechanical Engineering – Engineering Mechanics

Poster Presentation Competition

  1. 1st Place: Matthew Kilgas, Department of Kinesiology and Integrative Physiology
  2. 2nd Place: Brian Page, Department of Mechanical Engineering – Engineering Mechanics
  3. 3rd Place: Zichen Qian, Department of Biomedical Engineering
  4. People’s Choice: Mugdha Priyadarshini, Department of Civil and Environmental Engineering

Graduate Student Service Awards

  1. Gorkem Asilioglu, Department of Computer Science
  2. Hossein Tavakoli, Department of Civil and Environmental Engineering
  3. Kate Glodowski, Department of Kinesiology and Integrative Physiology
  4. Erin Pischke, Department of Social Sciences

The GRC is held each year by the Graduate Student Government at Michigan Tech.

New ideas, cutting edge research and innovative solutions coming from U.P.

HOUGHTON — New ideas, cutting edge research, innovative solutions. ABC 10’s Keweenaw Bureau Reporter Rick Allen has more on the latest research projects by Michigan Tech graduate students.

Underwater researchers will be interested in a less costly, more maneuverable glider that can be used in Lake Superior.

MTU Mechanical Engineering PhD Student Donna Fard said,

They are shallow–water gliders, meaning that we can use them in the lake. What we have so far, they’re all ocean–going gliders.

Read more and watch the video at ABC10 UP, by Rick Allen.

Zhao Group Provides Chapter on Tissue Engineered Skeletal Muscles

Tissue Engineering and Nano TheranosticsCaleb Vogt, Mitchell Tahtinen, and Feng Zhao have provided the first chapter to a book entitled “Tissue Engineering and Nano Theranostics” (ISBN: 978-981-3149-18-2). World Scientific Publisher. 2017. The book provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy.

The chapter is “Engineering Approaches for Creating Skeletal Muscle,” and it highlights the significant impact of stem cells in skeletal muscle engineering and regeneration.

About the authors:

  • Feng Zhao is an Associate Professor in the Department of Biomedical Engineering.
  • Caleb Vogt and Mitchell Tahtinen were undergraduate researchers in the Zhao lab.
  • Caleb is currently in the graduate program of the University of Minnesota.
  • Mitchell is currently a master’s student in the Department of Mathematical Sciences at Michigan Tech. He still conducts research in the Zhao lab.

Budget News on H-STEM Engineering and Health Technologies Complex

H-STEMGovernor Snyder mentioned the project during his Budget Proposal Speech on February 8, 2017.

The $39.6M complex would contribute to Human-centered research, development and education for its students by developing therapeutic devices, sensors, instruments, preventive strategies and a health technologies-related workforce.

Read more at WLUC TV6, by Alyssa Barker.

Michigan Tech Board of Trustees Approves 5-year Capital Outlay Plan

The complex will support Michigan Tech’s integrated educational programs that apply engineering and science to problems related to the human condition. The University’s unique technological niche places Tech in an ideal position to contribute to human-centered research, development and education for its students by developing therapeutic devices, sensors, instruments, preventive strategies and a health technologies-related workforce. The complex will permit teams of researchers and students from Biomedical Engineering, Chemical Engineering, Mechanical Engineering, Electrical and Computer Engineering, Materials Science and Engineering, Biology, Chemistry, Cognitive and Learning Sciences, Computer Science, and Kinesiology and Integrative Physiology to work together in flexible lab spaces with shared equipment.

Read more at Michigan Tech News, by Jennifer Donovan.

Zhao Group Reviews Natural Extracellular Matrix Approaches

Zhao Natural ECM

Feng Zhao and her research group were invited to review the current biomanufacturing approaches that utilize either native tissue or cell-derived natural extracellular matrix in the field of cellular and tissue engineering.

The paper discusses the existing challenges for translational application of extracellular matrix-based products and the potential resolutions.

Natural extracellular matrix for cellular and tissue biomanufacturing. Qi Xing, Zichen Qian, Wenkai Jia, Avik Ghosh, Mitchell Tahtinen, Feng Zhao F. ACS Biomaterials Science & Engineering.

DOI: 10.1021/acsbiomaterials.6b00235

Kristina Rushlau Addresses Midyear Commencement

Midyear Commencement 2016Nearly 350 bachelor’s, master’s and PhD recipients are expected to take part in Michigan Technological University’s Midyear Commencement Saturday. Ceremonies take place at 10:30 a.m. Dec. 17, 2016, in the Wood Gym of the Student Development Complex.

Kristina Rushlau will deliver the student address. A Kalamazoo native, Rushlau graduates with a BS in Environmental Engineering. During her time at Michigan Tech, she participated in Mind Trekkers, the Society of Environmental Engineers and many other activities. She hopes to start her career in environmental engineering preferably in the Detroit Area.

Among the class of 2016 is Ashley VanSumeren from Goodrich, Michigan, who is graduating with a double major in Biomedical Engineering and Exercise Science. VanSumeren says she’s been heavily involved in undergraduate research since her sophomore year. Thanks to a scholarship from the Pavlis Honors College and Portage Health Foundation, she was able to conduct her own research project.

I looked at how the muscles of the legs and trunk contribute to seated upper body exercise. —Ashley VanSumeren

VanSumeren presented the results of her research at the Undergraduate Research Expo last march and at the Life Science and Technology Institute Research Forum in October. At the latter, she received the Grand Prize in the undergraduate division.

Michigan Tech is a family affair for VanSumeren whose parents and brother are alumni. She says she initially had “kind of sworn off” Tech because she didn’t want to appear to be “copying” her family. A visit during her senior year of high school (while en route to visit her first choice school) changed her mind. She said the opportunities she’s had in four years, including working with Olympic athletes for a senior design project, showed her that Tech was indeed the right choice.

The future is a little less clear for VanSumeren, who is planning to pursue a master’s degree in kinesiology with an emphasis on biomechanics.

I haven’t decided on a school yet, but have applied to schools across the country and in Canada. Following my master’s, I hope to get a job in a biomechanics research lab, either for a shoe company or a sport performance company.

She says she hasn’t ruled out continuing her education to earn a PhD.

Original story by Mark Wilcox.

Students look to the future after successful tenure at MTU

While earning her degree in Mechanical Engineering. Reagan May found time to be a racecar driver.

Two years ago, I was the Super Late Model Track champion in Plover, Wisconsin, followed up this past season with it in second in points. So, I’m excited to graduate, start my career as an engineer and continue racing throughout the rest of my life. —Reagan May

Ashley VanSumeren didn’t have much free time, she was double majoring in Biomedical Engineering and Exercise Science.

I got used to it. I also ended up getting a job on campus doing undergraduate research, so I really learned how to balance between class, work and research. —Ashley VanSumeren

Read more and watch the video at ABC10 News, by Rick Allen.

ABC10 Fall 2016 Commencement

Engineering Researchers Participate in TechTalks 2016

Kazuya Tajiri Tweet
Kazuya Tajiri Tweet

TechTalks 2016

Michigan Tech Research Forum
Faculty Research on Speed Dial

VIEW THE PHOTO ALBUM

The Michigan Tech Research Forum is a new University presentation series showcasing the work of Michigan Tech faculty, postdocs, and researchers.

On Thursday, November 10, 2016, several researchers gave two minute presentations for the inaugural TechTalks session of the Michigan Tech Research Forum. Five of the 13 researchers presented work from engineering disciplines:

  • Andrew Barnard– Mechanical Engineering-Engineering Mechanics: “Solid State Sound—A Hot Topic”
  • Paul Sanders– Materials Science and Engineering: “Rapid Metal Design”
  • Kazuya Tajiri– Mechanical Engineering-Engineering Mechanics: “Two-Phase Transport in Proton Exchange Membrane Fuel Cells”
  • Hector Moncada-Hernandez- Biomedical Engineering: “Point-of-Care Microfluidic Device for Blood Typing”
  • Ye Sarah Sun– Mechanical Engineering-Engineering Mechanics: “Wearable Electronics, Human-Centered Monitoring”

Michigan Tech Research Forum events are presented by the Office of the Provost and Vice President for Academic Affairs in coordination with the Office of the Vice President of Research.

Additional TechTalks sessions are coming up in Spring 2017. Interested in nominating yourself or others? Use this online form.

Browse the Twitter conversations in “TechTalks 2016: Take One,” by Allison Mills.

On Thursday, December 1, 2016, the second set of presentations included the following from engineering research faculty:

Jeff Naber
Department of Mechanical Engineering-Engineering Mechanics
APS LABS (Advanced Power Systems Research Center)

Michael Mullins
Department of Chemical Engineering
Electrospun Nanofibers as Neural Guidance Scaffolds

Feng Zhao
Department of Biomedical Engineering
Stem Cell and Tissue Engineering Research

Chad Deering
Department of Geological and Mining Engineering and Sciences
Ignimbrites to Batholiths

Darrell Robinette
Department of Mechanical Engineering-Engineering Mechanics
Gearing for Future Connectivity

Trisha Sain
Department of Mechanical Engineering-Engineering Mechanics
Mechanics of Soft Polymers

Browse the Twitter conversations in “TechTalks 2016: Take Two,” by Allison Mills.

IRES Denmark: Summer 2017 Research Opportunities for Students

IRES Denmark

International Research Experience for Students (IRES)
Biosensor Development, Summer 2017

Aarhus University in Denmark and Michigan Technological University offer summer research opportunities in Denmark from May to July 2017.

Explore sensor development and biomarker discovery to improve detection of cancer, malaria, and more with this international research opportunity.

Students in all years are welcome to apply, however, research experience is desirable for applicants. Desired majors include chemical engineering, biomedical engineering, chemistry, biology, and biochemistry. Four undergraduate and one graduate student will be accepted into the program. Applications are due by February 17, 2017.

The program will last for a total of 8 weeks, beginning in May and ending in July. This includes a 1 week orientation at Michigan Tech. A $4500 stipend will be provided, along with housing and travel.

LEARN MORE.